To study the effect of Modified Shentong Zhuyu Decoction(身痛逐瘀汤加味)assisting Tuina therapy for chronic frozen shoulder on the changes of bradykinin(BK)and interleukin-1β(IL-1β)in patients.
One hundred patients with chronic frozen shoulder admitted to the Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine from May 2022 to April 2023 were selected,and were divided into the Tuina group and the Modified Shentong Zhuyu Decoction group by the randomized numerical method. The Tuina group was treated with Tuina therapy,and the Modified Shentong Zhuyu Decoction group was treated with Modified Shentong Zhuyu Decoction on the basis of Tuina therapy,and the clinical effects of the two groups were analyzed.
The total effective rate was 96.00%(clinical cure rate 28.00% +significant effect rate 42.00% +effective rate 26.00%)in the Modified Shentong Zhuyu Decoction group was higher than that(84.00%)(clinical cure rate 18.00%+significant effect rate 36.00%+effective rate 30.00%)in the Tuina group,with a significant difference(P<0.05). Before treatment,there was no difference in bradykinin(BK),5-hydroxytryptamine(5-HT)or inflammatory factors between the Tuina group and the Modified Shentong Zhuyu Decoction group(P>0.05). The levels of BK,interleukin-18(IL-18),5-HT,IL-1β,interleukin-32(IL-32)and granulocyte-macrophage colony-stimulating factor(GM-CSF)were lower in the Tuina and Modified Shentong Zhuyu Decoction groups compared with those before treatment(P<0.05),and they were lower in the Modified Shentong Zhuyu Decoction group compared with those in the Tuina group(P<0.05). Before treatment,there was no difference between the McGill Pain Questionnaire score and American Shoulder and Elbow Surgeons'Score(ASES)in the Tuina group and the Modified Shentong Zhuyu Decoction group(P>0.05). McGill scores were lower in the Tuina and Modified Shentong Zhuyu Decoction groups than those before treatment(P<0.05),and lower in the Modified Shentong Zhuyu Decoction group than those in the Tuina group(P<0.05). ASESscores were lower(P<0.05)in the Tuina and Modified Shentong Zhuyu Decoction groups than those before treatment,and the score in the Modified Shentong Zhuyu Decoction group higher(P<0.05)than that in the Tuina group.
Modified Shentong Zhuyu Decoction assisting Tuina therapy for chronic frozen shoulder can reduce the expressions of BK,5-HT and Inflammatory Factors and improve the daily living ability.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |