Full
Outline
To observe the clinical efficacy of Modified Guizhi Jia Gegen Tang (桂枝加葛根汤) Combined with Fuzi Tang (附子汤) in the treatment of cervical spondylosis of neck of wind-cold-dampness type.
Sixty patients with cervical spondylosis of neck of wind-cold-dampness type who visited the outpatient department of the Rehabilitation Medicine Department of the First Affiliated Hospital of Guangxi University of Chinese Medicine from June 2022 to March 2023 were divided into two groups by the random number table method, with 30 cases in each group. The patients in the control group were treated with celecoxib capsules according to the conventional Western medicine treatment plan, while those in the observation group were treated with the Modified Guizhi Jia Gegen Tang combined with Fuzi Tang by oral administration. Both groups were treated once a day, and 5 treatments constituted one course of treatment, with a total of two courses of treatment. Then, follow-up visits were carried out before treatment, after one and two courses of treatment, and one month later. Scale scores were conducted at these four time points to judge the improvement degree of the patients' symptoms and signs and the excellent and good rate of the clinical efficacy, etc.
After one and two courses of treatment, the range of motion (ROM) of cervical joints, short-form McGill pain questionnaire (SF-MPQ) scores, neck disability index (NDI), and cervical spondylosis clinical assessment scale (CASCS) scores of the patients in both groups were lower than those before treatment. Compared with those in the control group, the scores in the observation group decreased significantly, and the differences were statistically significant (P<0.05). The average scores of the Tanaka-Yoshihisa Cervical Spondylosis Symptom Scale of the patients in both groups were higher than those before treatment, and the increase in the observation group was more significant than that in the control group, and the differences were statistically significant (P<0.05). After two courses of treatment, the total clinical effective rate of the observation group was 100%, which was better than 90.00% of the control group. Moreover, it was found after follow-up that there were no significant changes in the results of the McGill pain scale, the 20-point method of the Tanaka-Yoshihisa Cervical Spondylosis Symptom Scale, NDI and CASCS scores of the observation group compared with those after the second course of treatment, and the differences were statistically significant (P<0.05).
Modified Guizhi Jia Gegen Tang combined with Fuzi Tang and the Western medicine celecoxib capsules can effectively relieve the symptoms and signs of cervical spondylosis of neck. Modified Guizhi Jia Gegen Tang combined with Fuzi Tang has a more significant treatment effect and advantages in relieving pain and improving dysfunction, and has a long-lasting curative effect.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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