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Outline
Kaixin Powder (开心散) is simple in composition and has great efficacy, which is mainly used to treat emotional and cognitive disorders. Thoroughly analyzing the essence of the composition of Kaixin Powder is beneficial for the “inheritance” and “innovation” of classic traditional Chinese medicine formulas. In addition to being commonly used to treat Alzheimer's disease and depression, Kaixin Powder is also used to treat disorders of glucose and lipid metabolism, including coronary heart disease and angina pectoris. Kaixin Powder revolves around the basic pathogenesis of “spleen dampness and kidney dryness”, using a combination of sweet, bitter and spicy ingredients, which is in line with the basic theory of traditional Chinese medicine, as well as the core pathogenesis of disorders in glucose and lipid metabolism and related diseases such as “spleen dysfunction, kidney Qi deficiency, and phlegm dampness”. The research on the intervention of Kaixin Powder and its components in glucose and lipid metabolism disorders mainly focuses on intervening in the hypothalamic-pituitary-adrenal (HPA) axis, regulating gut microbiota, anti chronic inflammation and antioxidant stress. This article can provide reference and inspiration for Kaixin Powder and its components to intervene in glucose and lipid metabolism disorders and expand their clinical applications.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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