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Dahuang (Rhei Radix et Rhizoma) and Its Active Ingredients in Treatment of Mental Diseases
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Sihan ZHAO1, Aineng PENG2, Yonghou ZHAO1, Hao ZHANG2, Jianbo CHAI1
Chinese Archives of Traditional Chinese Medicine | 2026, 44(7) : 105 - 112
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(7): 105-112
• Target on National Project •
Dahuang (Rhei Radix et Rhizoma) and Its Active Ingredients in Treatment of Mental Diseases
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Sihan ZHAO1, Aineng PENG2, Yonghou ZHAO1, Hao ZHANG2, Jianbo CHAI1
Affiliations
  • 1.Heilongjiang Mental Hospital, Harbin 150036, Heilongjiang, China
  • 2.Heilongjiang University of Chinese Medicine, Harbin 150040, Heilongjiang, China
Published: 2026-07-10 doi: 10.13193/j.issn.1673-7717.2026.07.020
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Mental illnesses are diseases that seriously affect the physical and mental health of human beings and their social functions. Traditional Chinese medicine has important advantages in preventing and treating mental illness. It can “prevent illness before it occurs”, effectively relieve many “indescribable” symptoms, and alleviate various side effects caused by Western medicine. Dahuang (Rhei Radix et Rhizoma) is a common traditional Chinese medicine, which is widely used in the treatment of mental diseases, such as schizophrenia, depression, insomnia, etc. Dahuang (Rhei Radix et Rhizoma)-related formulas, such as Chengqi Tang (承气汤), Dachaihu Tang (大柴胡汤) and Chaihu Jia Longgumuli Tang (柴胡加龙骨牡蛎汤), are commonly used by ancient physicians in the treatment of mental diseases. Modern pharmacological mechanisms show that the anthraquinone components in Dahuang (Rhei Radix et Rhizoma) are the core components of its function. It has been shown that Dahuang (Rhei Radix et Rhizoma) components help to improve inflammatory damage, neurodevelopmental damage, neurotransmitter disorders, intestinal flora disorders and sexual hormone disturbance in psychiatric disorders, and that Dahuang (Rhei Radix et Rhizoma) monomers such as rheum emodin have exerted a stable effect on improving the pathological damage of psychiatric disorders, and that research on Dahuang (Rhei Radix et Rhizoma) components and dosage forms is becoming more and more in-depth, which is expected to be more widely used in the treatment of mental illness in the future. The active ingredients, clinical studies and pharmacological mechanisms of Dahuang (Rhei Radix et Rhizoma) in the treatment of psychiatric disorders were systematically discussed with a view to providing references for the treatment and research of psychiatric disorders.

Dahuang (Rhei Radix et Rhizoma)  /  mental disorders  /  active components  /  depression  /  schizophrenia
赵思涵, 彭爱能, 赵永厚, 张浩, 柴剑波. 大黄及其有效成分治疗精神疾病研究进展. 中华中医药学刊, 2026 , 44 (7) : 105 -112 . DOI: 10.13193/j.issn.1673-7717.2026.07.020
Sihan ZHAO, Aineng PENG, Yonghou ZHAO, Hao ZHANG, Jianbo CHAI. Dahuang (Rhei Radix et Rhizoma) and Its Active Ingredients in Treatment of Mental Diseases[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (7) : 105 -112 . DOI: 10.13193/j.issn.1673-7717.2026.07.020
Year 2026 volume 44 Issue 7
81
12
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doi: 10.13193/j.issn.1673-7717.2026.07.020
  • Online Date:2026-10-20
  • Published:2026-07-10
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    1.Heilongjiang Mental Hospital, Harbin 150036, Heilongjiang, China
    2.Heilongjiang University of Chinese Medicine, Harbin 150040, Heilongjiang, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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