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Research Progress on Mechanism of Anti-Tumor Action of Xiakucao (Prunellae Spica)
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Jie GAO1, Liheng LI1, 2, Yufei ZHANG1, Shurui ZHAO1, Yinuo LI1, Youcai YUAN1, Renshuai WANG1
Chinese Archives of Traditional Chinese Medicine | 2026, 44(8) : 188 - 194
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(8): 188-194
• Target on National Project •
Research Progress on Mechanism of Anti-Tumor Action of Xiakucao (Prunellae Spica)
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Jie GAO1, Liheng LI1, 2, Yufei ZHANG1, Shurui ZHAO1, Yinuo LI1, Youcai YUAN1, Renshuai WANG1
Affiliations
  • 1.Heilongjiang University of Chinese Medicine, Harbin 150040, Heilongjiang, China
  • 2.Heilongjiang Provincial Key Laboratory of Chinese Medicine Informatics, Harbin 150040, Heilongjiang, China
Published: 2026-08-10 doi: 10.13193/j.issn.1673-7717.2026.08.038
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Xiakucao (Prunellae Spica) is the dry ear of Xiakucao (Prunella vulgaris L.), and has the effect of clearing liver and reducing fire, brightening eyes, dispersing knot and reliving swelling. Modern pharmacological studies show that the active ingredients in Xiakucao (Prunellae Spica) can effectively inhibit tumor cell proliferation, invasion and metastasis, induce apoptosis and autophagy, block cell cycle and signaling, but also can improve the body immunity. For different types of tumors, it shows significant antagonistic effect, and has multiple components, multiple target and multi-pathway treatment advantages. This paper systematically reviewed the anti-tumor active components and their mechanism of action, and aimed to provide a powerful reference basis for further research and new drug development in the field of anti-tumor.

Xiakucao (Prunellae Spica)  /  active ingredient  /  anti-tumor  /  invasion and metastasis  /  cell cycle  /  signal transduction
高杰, 李力恒, 张宇飞, 赵淑睿, 李怡诺, 袁有才, 王仁帅. 夏枯草活性成分抗肿瘤作用机制的研究进展. 中华中医药学刊, 2026 , 44 (8) : 188 -194 . DOI: 10.13193/j.issn.1673-7717.2026.08.038
Jie GAO, Liheng LI, Yufei ZHANG, Shurui ZHAO, Yinuo LI, Youcai YUAN, Renshuai WANG. Research Progress on Mechanism of Anti-Tumor Action of Xiakucao (Prunellae Spica)[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (8) : 188 -194 . DOI: 10.13193/j.issn.1673-7717.2026.08.038
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Year 2026 volume 44 Issue 8
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doi: 10.13193/j.issn.1673-7717.2026.08.038
  • Online Date：2026-10-20
  • Published：2026-08-10
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    1.Heilongjiang University of Chinese Medicine, Harbin 150040, Heilongjiang, China
    2.Heilongjiang Provincial Key Laboratory of Chinese Medicine Informatics, Harbin 150040, Heilongjiang, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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