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Research Progress on Fresh, Raw and Processed Dihuang (Rehmanniae Radix) and Predictive Analysis of Its Quality Markers
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Mengqing YAN1, Hongwei ZHANG1, 2, Mengyun LIU1, 2, Hongwei LI1, 2, Mingsan MIAO2, 3, Jianguang ZHU1, 2, 3, Kai LI1, 2, Le KANG1, 2, 3
Chinese Archives of Traditional Chinese Medicine | 2026, 44(8) : 177 - 180
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(8): 177-180
• Target on National Project •
Research Progress on Fresh, Raw and Processed Dihuang (Rehmanniae Radix) and Predictive Analysis of Its Quality Markers
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Mengqing YAN1, Hongwei ZHANG1, 2, Mengyun LIU1, 2, Hongwei LI1, 2, Mingsan MIAO2, 3, Jianguang ZHU1, 2, 3, Kai LI1, 2, Le KANG1, 2, 3
Affiliations
  • 1.School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
  • 2.Henan University of Chinese Medicine, Inheritance Base of Traditional Chinese Medicine Concoction of State Administration of Traditional Chinese Medicine, Zhengzhou 450046, Henan, China
  • 3.Collaborative Innovation Center of Research and Development on the Whole Industry Chain of Yu-Yao, Zhengzhou 450046, Henan, China
Published: 2026-08-10 doi: 10.13193/j.issn.1673-7717.2026.08.036
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As one of the local medicinal herbs in Henan Province, the fresh product of Dihuang (Rehmanniae Radix) has the function of clearing heat and generating fluids, cooling blood and stopping bleeding. The raw product has the effect of clearing heat and cooling blood, nourishing Yin and generating fluids and the processed product has the function of replenishing blood and nourishing Yin and benefiting the essence and filling in the marrow. Currently, there is a single method for quality evaluation of Dihuang (Rehmanniae Radix), therefore, based on the traditional Chinese medicine theory that “the raw product is especially good”, “combination of raw and processed products”, the studies on the chemical composition and pharmacological effects of Dihuang (Rehmanniae Radix) before and after processing were summarized. Combined with the quality marker (Q-Marker) prediction analysis from the aspects of plant affinity and chemical constituents, traditional efficacy and clinical compatibility, traditional medicinal properties and material basis, concoction method and auxiliary material differences, blood components and pharmacokinetics, dihuangoside A, mauritiana glycoside, catalpol, stachyose, quercetin, baicalein, sanguinarol, polysaccharide, hesperidin, digitonin and dihuangoside D can be regarded as the most important chemical constituents in the traditional Chinese medicine, which can be used for the quality evaluation of Dihuang (Rehmanniae Radix), with the aim of providing a reference for the quality control study of Dihuang (Rehmanniae Radix), the guidance of clinical use and the development of new drugs.

Dihuang (Rehmanniae Radix)  /  fresh and raw  /  raw and cooked  /  quality markers
燕梦晴, 张宏伟, 刘梦云, 李红伟, 苗明三, 朱建光, 李凯, 康乐. 地黄鲜用、生用、熟用研究进展及其质量标志物（Q-Marker）的预测分析. 中华中医药学刊, 2026 , 44 (8) : 177 -180 . DOI: 10.13193/j.issn.1673-7717.2026.08.036
Mengqing YAN, Hongwei ZHANG, Mengyun LIU, Hongwei LI, Mingsan MIAO, Jianguang ZHU, Kai LI, Le KANG. Research Progress on Fresh, Raw and Processed Dihuang (Rehmanniae Radix) and Predictive Analysis of Its Quality Markers[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (8) : 177 -180 . DOI: 10.13193/j.issn.1673-7717.2026.08.036
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Year 2026 volume 44 Issue 8
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doi: 10.13193/j.issn.1673-7717.2026.08.036
  • Online Date：2026-10-20
  • Published：2026-08-10
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    1.School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
    2.Henan University of Chinese Medicine, Inheritance Base of Traditional Chinese Medicine Concoction of State Administration of Traditional Chinese Medicine, Zhengzhou 450046, Henan, China
    3.Collaborative Innovation Center of Research and Development on the Whole Industry Chain of Yu-Yao, Zhengzhou 450046, Henan, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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