Xiaobanxia Decoction (小半夏汤) is a classic prescription for the treatment of “vomiting” in the Synopsis of the Golden Chamber written by ZHANG Zhongjing in the Eastern Han Dynasty. It is often used clinically to treat vomiting of various syndromes. Chemotherapy-induced nausea and vomiting (CINV) is one of the most common and unbearable adverse reactions in the cancer patients after chemotherapy. By searching the relevant literature on the clinical research, pharmacology and animal experimental research of Xiaobanxia Decoction in the treatment of CINV, the research group has found that both clinical research and experimental research can prove its good efficacy in the treatment of CINV. The clinical observation has found that Xiaobanxia Decoction often alone or combined with western medicine or combined with acupuncture, acupoint application and other traditional Chinese medicine treatments can effectively treat CINV, and the toxic and side effects are few, and the patients are easy to accept. The experimental study has found that the mechanism of Xiaobanxia Decoction in the treatment of CINV is mainly related to its regulation of inflammatory factors, regulating multiple neurotransmitter systems and gastrointestinal motility function, induction of apoptosis and so on. This paper discussed the treatment of CINV with Xiaobanxia Decoction from three aspects: theoretical research, clinical experiment and mechanism of action. The purpose of this paper was to study the progress of Xiaobanxia Decoction in the treatment of CINV, so as to provide more scientific basis and reference for clinical treatment.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |