It explored the pathogenesis and therapeutic strategies for chronic heart failure (CHF) based on the theory of “Yin and Yang Link Vessels”. In Traditional Chinese Medicine (TCM), the key pathogenesis of CHF involves an imbalance of Qi, blood, Yin and Yang, leading to a pathological pattern of root deficiency and excess manifestations characterized by the intermingling of deficiency, blood stasis and fluid retention. Building upon existing CHF theories (e.g., Qi deficiency with blood stasis, Yang deficiency with water overflow and heart-kidney Yang deficiency), this study further proposed that the disharmony of the Yin and Yang Link Vessels was a critical pathogenic mechanism. Accordingly, a “harmonizing the link vessels and unblocking collaterals” therapeutic model was established, employing a comprehensive treatment approach that included boosting Qi and warming Yang, activating blood circulation and unblocking collaterals, and resolving fluid retention and promoting diuresis, with an emphasis on individualized and dynamic pattern differentiation. This theory provides novel insights for TCM diagnosis and treatment of CHF, expands the application of TCM theories in cardiovascular diseases, and holds significant clinical value.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |