Ischemic stroke is characterized by high disability rate,high mortality rate and high recurrence rate,and is the main cause of national death in China. At present,thrombolytic and surgical treatments are the main treatment pathways for ischemic stroke,but due to the limitations of various reasons,the expected therapeutic effects are often not achieved. The treatment of ischemic stroke through the combination of traditional Chinese and Western medicine has become a broad social consensus. The tonifying Qi and activating blood therapy,represented by Buyang Huanwutang,has demonstrated remarkable therapeutic effects in the treatment of ischemic stroke. Huanggqi(Astragali Radix),as a representative traditional Chinese medicine of the formula of tonifying Qi and activating blood,has the effects of tonifying Qi and “expelling evil blood”,and it is a commonly used traditional Chinese medicine in the treatment of ischemic stroke. Previous studies have confirmed that Huanggqi(Astragali Radix)can inhibit inflammation and oxidative stress,improve mitochondrial dysfunction and vascular endothelial dysfunction,and thus plays a therapeutic role in cardiovascular and cerebrovascular diseases. However,there is a lack of evidence-based and fundamental systematic discussion on the studies related to the treatment of ischemic stroke with Huanggqi(Astragali Radix). The aim of this paper is to provide a pharmacological basis for the wider application of Huanggqi(Astragali Radix)in the prevention and treatment of cerebrovascular diseases by systematically discussing the pharmacological effects of Huanggqi(Astragali Radix)in the prevention and treatment of Ischemic Stroke.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |