Home Journals Articles Updates About
CN
image
收藏切换
Research Progress on Mechanism of Effective Components of Huangqin（Scutellariae Radix）against Multiple Organ Fibrosis
收藏切换
Jian GAO, Xuanyu WU, Wenjia XIAN, Yutong ZOU, Cheng WU, Quanyu DU, Fei WANG
Chinese Archives of Traditional Chinese Medicine | 2026, 44(2) : 85 - 92
Less
收藏切换
Chinese Archives of Traditional Chinese Medicine | 2026, 44(2): 85-92
• Target on National Project •
Research Progress on Mechanism of Effective Components of Huangqin（Scutellariae Radix）against Multiple Organ Fibrosis
Full
Jian GAO, Xuanyu WU, Wenjia XIAN, Yutong ZOU, Cheng WU, Quanyu DU, Fei WANG
Affiliations
  • Hospital of Chengdu University of Traditional Chinese Medicine，Chengdu 610072，Sichuan，China
Published: 2026-02-10 doi: 10.13193/j.issn.1673-7717.2026.02.016
Outline
收藏切换

Organ fibrosis is a highly dynamic pathophysiological process that can affect multiple organs，characterized by excessive accumulation of extracellular matrix. The pathogenesis of fibrosis is complex，and in severe cases，it can lead to organ failure. Currently，there is a lack of specific drugs. In recent years，it is found that Huangqin（Scutellariae Radix）has shown positive effects in various organ fibrosis. Therefore，this study searched six commonly used biomedical databases and analyzed the literature on the treatment of fibrosis diseases with Huangqin（Scutellariae Radix）in the past 20 years. This study has found that the anti-fibrotic components of Huangqin（Scutellariae Radix）mainly include baicalin，baicalein，wogonoside，scutellarin，etc. Huangqin（Scutellariae Radix）mainly exerts its anti-fibrotic effect by inhibiting fibroblast transformation，preventing fibroblast proliferation，reducing extracellular matrix deposition，antioxidant stress and regulating fibrotic related pathways. In summary，Huangqin（Scutellariae Radix）is a potential anti-fibrotic drug with positive clinical significance.

baicalin  /  baicalein  /  oroxindin  /  oroxylin A  /  scutellarin  /  fibrosis
高鉴, 吴宣諭, 鲜文佳, 邹雨彤, 吴程, 杜全宇, 王飞. 黄芩有效成分抗多器官纤维化的研究进展. 中华中医药学刊, 2026 , 44 (2) : 85 -92 . DOI: 10.13193/j.issn.1673-7717.2026.02.016
Jian GAO, Xuanyu WU, Wenjia XIAN, Yutong ZOU, Cheng WU, Quanyu DU, Fei WANG. Research Progress on Mechanism of Effective Components of Huangqin（Scutellariae Radix）against Multiple Organ Fibrosis[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (2) : 85 -92 . DOI: 10.13193/j.issn.1673-7717.2026.02.016
Appendix
Less
Year 2026 volume 44 Issue 2
96
11
Cite this Article
BibTeX
Article Info
doi: 10.13193/j.issn.1673-7717.2026.02.016
  • Online Date：2026-10-14
  • Published：2026-02-10
Article Data
Affiliations
History
Affiliations
    Hospital of Chengdu University of Traditional Chinese Medicine，Chengdu 610072，Sichuan，China
References
Share
https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/10.13193/j.issn.1673-7717.2026.02.016
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62662699(Operation and Technical Support)
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House