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Research Progress of Chemical Composition and Pharmacological Effects of Daqingye（Isatidis Folium）and Its Quality Marker Prediction Analysis
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Liguo YANG1, 2, Xiwen SHEN1, 2, Wenlong BAO1, 2
Chinese Archives of Traditional Chinese Medicine | 2026, 44(2) : 46 - 57
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(2): 46-57
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Research Progress of Chemical Composition and Pharmacological Effects of Daqingye（Isatidis Folium）and Its Quality Marker Prediction Analysis
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Liguo YANG1, 2, Xiwen SHEN1, 2, Wenlong BAO1, 2
Affiliations
  • 1.College of Mongolian Medicine and Pharmacy，Inner Mongolia Minzu University，Tongliao 028000，Inner Mongolia，China
  • 2.National and Local Joint Engineering Research Center for Mongolian Medicine Research and Development，Tongliao 028000，Inner Mongolia，China
Published: 2026-02-10 doi: 10.13193/j.issn.1673-7717.2026.02.009
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Daqingye（Isatidis Folium）is the dried leaves of Songlan（Isatis indigotica Fort）. Its chemical composition mainly includes alkaloids，organic acids，flavonoids，lignans，etc.，with antiviral，anti-endotoxin，anti-inflammatory，antibacterial，antioxidant，anti-tumor，immune regulation and other effects. Based on the research progress of chemical components and pharmacological effects of Daqingye（Isatidis Folium），the quality markers of Daqingye（Isatidis Folium）were predicted and analyzed from the aspects of transmission and traceability，plant genetics，chemical component specificity，effectiveness and measurability. It is predicted that indirubin，indigo，tryptanthrin，4（3H）- quinazolinone，1，2，2＇-tri-O-E-sinapoyl-β-gentiobiose，1，2，6＇-tri-O-E-sinapoylgentiobiose，isovitexin，isoscoparin and lariciresinol can be used as the candidate compounds of the quality markers of Daqingye（Isatidis Folium），which can provided a reference for improving the quality evaluation system of Daqingye（Isatidis Folium）.

Daqingye（Isatidis Folium）  /  chemical composition  /  pharmacological effects  /  quality markers
杨立国, 沈细文, 包文龙. 大青叶化学成分和药理作用研究进展及其质量标志物预测分析. 中华中医药学刊, 2026 , 44 (2) : 46 -57 . DOI: 10.13193/j.issn.1673-7717.2026.02.009
Liguo YANG, Xiwen SHEN, Wenlong BAO. Research Progress of Chemical Composition and Pharmacological Effects of Daqingye（Isatidis Folium）and Its Quality Marker Prediction Analysis[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (2) : 46 -57 . DOI: 10.13193/j.issn.1673-7717.2026.02.009
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Year 2026 volume 44 Issue 2
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doi: 10.13193/j.issn.1673-7717.2026.02.009
  • Online Date：2026-10-14
  • Published：2026-02-10
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    1.College of Mongolian Medicine and Pharmacy，Inner Mongolia Minzu University，Tongliao 028000，Inner Mongolia，China
    2.National and Local Joint Engineering Research Center for Mongolian Medicine Research and Development，Tongliao 028000，Inner Mongolia，China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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