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Research Progress of Zhenwu Decoction（真武汤）and Its Active Ingredients in Chronic Kidney Disease
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Kaili CHEN1, 2, Linqi ZHANG1, Changbin XIAO1, 2, Siyu HUANG1, 2, Chenpeng SHI1, 2, Yiting SUN1, 2
Chinese Archives of Traditional Chinese Medicine | 2026, 44(2) : 162 - 168
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(2): 162-168
• Target on National Project •
Research Progress of Zhenwu Decoction（真武汤）and Its Active Ingredients in Chronic Kidney Disease
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Kaili CHEN1, 2, Linqi ZHANG1, Changbin XIAO1, 2, Siyu HUANG1, 2, Chenpeng SHI1, 2, Yiting SUN1, 2
Affiliations
  • 1.The First Affiliated Hospital of Henan University of Chinese Medicine，Zhengzhou 450000，Henan，China
  • 2.The First Clinical Medical College of Henan University of Chinese Medicine，Zhengzhou 450046，Henan，China
Published: 2026-02-10 doi: 10.13193/j.issn.1673-7717.2026.02.029
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Chronic kidney disease is a serious challenge to global public health. As one of the classic prescriptions of medical saints，Zhenwu Decoction（真武汤），as one of the classic prescriptions of medical sages，is used to tonify and purge and promote diuresis，and is mainly used for treating Yang deficiency and water flooding syndrome. In clinical reports，its modified formulas or combination with traditional Chinese medicine external treatment or combination with Western medicine are usually used to treat a variety of chronic kidney diseases such as nephrotic syndrome，chronic glomerulonephritis，idiopathic membranous nephropathy，IgA nephropathy，diabetic kidney disease，lupus nephritis，hepatitis B virus associated glomerulonephritis，chronic renal failure and cardiorenal syndrome. In addition，the main active ingredients of the drugs in Zhenwu Decoction have demonstrated a variety of pharmacological effects such as antioxidant，anti-inflammation，immune regulation，anti-apoptosis，promoting autophagy，inhibiting iron death，anti-fibrosis，diuretic and regulating intestinal flora. This article summarized the relevant literature reports and systematically analyzed the clinical trials of Zhenwu Decoction，the pharmacological effects of its active ingredients in chronic kidney disease and the basic animal experiments，aiming to provide support for the clinical standardized application and pharmacological research of Zhenwu Decoction.

Zhenwu Decoction（真武汤）  /  active ingredient  /  chronic kidney disease  /  research progress
陈凯丽, 张琳琪, 肖长斌, 黄思雨, 史晨鹏, 孙依婷. 真武汤及其单味药有效成分在慢性肾脏疾病中的研究进展. 中华中医药学刊, 2026 , 44 (2) : 162 -168 . DOI: 10.13193/j.issn.1673-7717.2026.02.029
Kaili CHEN, Linqi ZHANG, Changbin XIAO, Siyu HUANG, Chenpeng SHI, Yiting SUN. Research Progress of Zhenwu Decoction（真武汤）and Its Active Ingredients in Chronic Kidney Disease[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (2) : 162 -168 . DOI: 10.13193/j.issn.1673-7717.2026.02.029
Appendix
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Year 2026 volume 44 Issue 2
91
15
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doi: 10.13193/j.issn.1673-7717.2026.02.029
  • Online Date：2026-10-14
  • Published：2026-02-10
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Affiliations
    1.The First Affiliated Hospital of Henan University of Chinese Medicine，Zhengzhou 450000，Henan，China
    2.The First Clinical Medical College of Henan University of Chinese Medicine，Zhengzhou 450046，Henan，China
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表12种不同金属材料的力学参数
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Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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