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Research Progress on Chemical Composition and Biological Activity of Zaojiaoci（Gleditsiae Spina）and Prediction Analysis of Quality Marker
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Qin ZHA1, 2, Tao ZOU2, Peng ZOU2, Xu ZHANG3, Pengsheng HONG3, Houxi XIONG1, Xiangyu ZHANG2, Xinqian ZHAO3
Chinese Archives of Traditional Chinese Medicine | 2026, 44(2) : 34 - 45
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(2): 34-45
• Target on National Project •
Research Progress on Chemical Composition and Biological Activity of Zaojiaoci（Gleditsiae Spina）and Prediction Analysis of Quality Marker
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Qin ZHA1, 2, Tao ZOU2, Peng ZOU2, Xu ZHANG3, Pengsheng HONG3, Houxi XIONG1, Xiangyu ZHANG2, Xinqian ZHAO3
Affiliations
  • 1.The Key Laboratory for Health Industry of Bijie，Bijie Medical College，Bijie 551700，Guizhou，China
  • 2.Bijie Institute of Chinese Materia Medica，Bijie 551700，Guizhou，China
  • 3.Bijie Hospital，Zhejiang Provincial People＇s Hospital，Bijie 551700，Guizhou，China
Published: 2026-02-10 doi: 10.13193/j.issn.1673-7717.2026.02.008
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Zaojiaoci（Gleditsiae Spina）is a dry thorn of the leguminous plant Zaojia（Gleditsia sinensis Lam），which has the function of reducing swelling and supporting poison，expelling pus and killing insects. The main chemical components include polyphenols，flavonoids，terpenoids，sterols，etc. Modern pharmacology indicates that Zaojiaoci（Gleditsiae Spina）has various pharmacological effects such as anti-tumor，anti-bacterial，anti-coagulation，immune regulation and anti-allergy effects. However，there is no index component for quality control in recorded of Zaojiaoci（Gleditsiae Spina）in Chinese Pharmacopoeia. Furthermore，there is no systematical standard basis for interpreting the relationship between its “composition” and “quality”. Therefore，the chemical constituents and pharmacological effects of Zaojiaoci（Gleditsiae Spina）were summarized. According to the concept of quality marker（Q-Marker），the Q-Markers of Zaojiaoci（Gleditsiae Spina）were predicted from the aspects of plant relatives，chemical composition specificity，composition and efficacy correlation，traditional medicinal properties，compound compatibility and chemical measurement of chemical composition，which provided the basis for the quality evaluation and rational development and utilization of Gleditsiae Spina.

Zaojiaoci（Gleditsiae Spina）  /  quality marker（Q-Markers）  /  chemical composition  /  biological activity  /  anti-tumor
查钦, 邹涛, 邹鹏, 张旭, 洪鹏升, 熊厚溪, 张翔宇, 赵欣黔. 皂角刺化学成分、生物活性研究进展及其质量标志物预测分析. 中华中医药学刊, 2026 , 44 (2) : 34 -45 . DOI: 10.13193/j.issn.1673-7717.2026.02.008
Qin ZHA, Tao ZOU, Peng ZOU, Xu ZHANG, Pengsheng HONG, Houxi XIONG, Xiangyu ZHANG, Xinqian ZHAO. Research Progress on Chemical Composition and Biological Activity of Zaojiaoci（Gleditsiae Spina）and Prediction Analysis of Quality Marker[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (2) : 34 -45 . DOI: 10.13193/j.issn.1673-7717.2026.02.008
Appendix
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Year 2026 volume 44 Issue 2
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doi: 10.13193/j.issn.1673-7717.2026.02.008
  • Online Date：2026-10-14
  • Published：2026-02-10
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Affiliations
    1.The Key Laboratory for Health Industry of Bijie，Bijie Medical College，Bijie 551700，Guizhou，China
    2.Bijie Institute of Chinese Materia Medica，Bijie 551700，Guizhou，China
    3.Bijie Hospital，Zhejiang Provincial People＇s Hospital，Bijie 551700，Guizhou，China
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https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/10.13193/j.issn.1673-7717.2026.02.008
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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