To observe the effect of Tibetan medicine Qishiwei Zhenzhu Pill(七十味珍珠丸)on the improvement of nerve and limb function in patients with stroke recovery.
From March 2023 to February 2024, 92 patients with convalescent stroke were selected as the research subjects. According to the random principle and the ratio of 1:1, they were divided into two groups. The control group(46 patients)in were treated with conventional western medicine, and the observation group(46 patients)were treated with Qishiwei Zhenzhu Pill on the basis of the control group for 8 weeks. The total effective rate, improvement of nerve and limb function, cerebral blood perfusion index and incidence of adverse drug reactions were compared between the two groups.
The total effective rate of the observation group was 95.65%, which was significantly higher than that of the control group(82.61%)(P < 0.05). 8 weeks after treatment, the National Institute of Health stroke scale(NIHSS)score of the observation group was significantly lower than that of the control group, and the difference was statistically significant(P < 0.05). 8 weeks after treatment, the upper limb, lower limb score and Fugl-Meyer motor function assessment(FMA)total score of the observation group were significantly increased, and the scores of the observation group were significantly higher than those of the control group(P < 0.05). There was no significant difference in cerebral blood flow perfusion indexes between the two groups before treatment(P > 0.05). 8 weeks after treatment, the peak systolic velocity(PSV)and mean velocity(TMV)of the two groups increased, and the resistance index(RI)decreased, and these indexes of the observation group were better than those of the control group(P < 0.05).
Tibetan medicine Qishiwei Zhenzhu Pill has a positive therapeutic effect on patients with stroke recovery, and can improve the cerebral blood flow perfusion, the nerve and limb function of patients, and has good safety, which is worthy of application.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |