To explore the clinical effect of Modified Shuqi Dingtong Decoction（疏气定痛汤）according to syndrome differentiation combined with sensitive antibiotics in treating chronic pelvic inflammatory disease and its influence on inflammatory factors.

A total of 108 patients with chronic pelvic inflammation admitted to the hospital from December 2020 to December 2023 were selected as the study object and were divided into observation group and control group. The control group were treated with sensitive antibiotics, and the observation group took Shuqi Dingtong Decoction according to syndrome differentiation on the basis of the control group. The clinical efficacy of the treatment, inflammatory factor indicators（interleukin-6, hypersensitive C-reactive protein）, TCM syndrome integration and adverse reactions of the two groups were observed and compared.

There was no significant difference between the two groups before treatment（P > 0.05）. Both groups obtained certain clinical therapeutic effect. The clinical response rate of the observation group was significantly higher than that of the control group（P < 0.05）. After treatment, The serum levels of interleukin-6 and hypersensitive C-reactive protein in two groups were decreased compared with those before treatment. Moreover, the levels in the observation group were significantly lower than those in the control group（P < 0.05）. After treatment, the symptom and sign scores of both groups decreased compared to those before treatment, and the scores of the observation group were significantly lower than those of the control group（all P < 0.05）.

The clinical effect of sensitive antibiotics combined with Modified Shuqi Dingtong Decoction according to syndrome differentiation is significant. It can improve the levels of inflammatory factors in patients, with relatively mild and controllable side effects and has certain clinical value.