To study the effects of Qingjin Huatan Decoction（清金化痰汤）and Qianjin Weijian Decoction（千金苇茎汤）on patients with bronchiectasis and infection.

A total of 106 patients with bronchiectasis and infection admitted to the hospital from April 2022 to April 2024 were selected as the study objects. The patients were divided into two groups by random number table method. Fifty-three patients receiving conventional western medicine treatment were established as the control group, on the basis of conventional western medicine, 53 patients who were treated with Qingjin Huatan Decoction and Qianjin Weijian decoction as the experiment group. Both groups were treated for 2 weeks. After treatment, the clinical efficacy, improvement degree of traditional Chinese medicine symptoms, lung function before and after treatment, sputum culture results, serum inflammatory markers, bronchiectasis severity index（BSI）score, lung lobe involvement and safety of the two groups were observed and compared.

The total effective rate of the experimental group was 96.23%, higher than that（84.91%）of the control group（P < 0.05）. After treatment, the scores of traditional Chinese medicine syndrome in both groups decreased, and compared with the control group, the experimental group showed a more significant decrease（P < 0.05）. After treatment, compared with the control group, the experimental group had higher levels of forced expiratory volume in the first second（FEV1）and the ratio of forced expiratory volume in the first second to lung capacity（FEV1/FVC）, and lower levels of BSI grading and lung lobe involvement（P < 0.05）. After treatment, compared with the control group, the experimental group had lower levels of white blood cell count（WBC）, C-reactive protein（CRP）and procalcitonin（PCT）（P < 0.05）. The pathogen detection rate of the experimental group was 11.32%, lower than that（32.08%）of the control group. The experimental group had fewer pathogen types（P < 0.05）. The adverse reaction rate of the experimental group was 5.66%, lower than that（20.75%）of the control group（P < 0.05）.

The combination of Qingjin Huatan Decoction and Qianjin Weijian Decoction has a good effect on the patients with bronchiectasis and infection, which can effectively reduce the clinical symptoms of patients, improve the lung function, reduce the inflammation and promote the rehabilitation of patients.