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Research Progress on Mechanism of Baicalin in Preventing and Treating Diabetic Nephropathy
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Xiaonian ZHANG, Aijun LIU, Jie ZHAO, Yuanming DIAO
Chinese Archives of Traditional Chinese Medicine | 2026, 44(4) : 24 - 27
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(4): 24-27
• Target on National Project •
Research Progress on Mechanism of Baicalin in Preventing and Treating Diabetic Nephropathy
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Xiaonian ZHANG, Aijun LIU, Jie ZHAO, Yuanming DIAO
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  • School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, Guangdong, China
Published: 2026-04-10 doi: 10.13193/j.issn.1673-7717.2026.04.006
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Diabetic nephropathy（DN）is one of the major microvascular complications of diabetes, and its pathogenesis is complex, involving apoptosis of renal tissue cells induced by hyperglycemic environment, abnormal activation of related enzymes, inflammation and oxidative stress, non-enzymatic glycosylation of proteins, abnormal deposition of extracellular matrix and abnormal lipid metabolism. Baicalin, a flavonoid compound extracted and isolated from the root of the traditional Chinese medicinal herb Huangqin（Scutellariae Radix）, possesses a wide range of pharmacological effects. In recent years, with the continuous exploration of new applications for traditional Chinese medicine, baicalin has been found to have apreventive and therapeutic effect on DN. Therefore, this article summarized and reviewed the research progress in the mechanism of baicalin preventing and treating DN in recent years, aiming to provide a theoretical basis and foundation for further research on the prevention and treatment of DN with baicalin in the future.

baicalin  /  prevention and treatment  /  diabetic nephropathy  /  mechanism of action  /  research progress
张小年, 刘爱军, 赵杰, 刁远明. 黄芩苷防治糖尿病肾病作用机制研究进展. 中华中医药学刊, 2026 , 44 (4) : 24 -27 . DOI: 10.13193/j.issn.1673-7717.2026.04.006
Xiaonian ZHANG, Aijun LIU, Jie ZHAO, Yuanming DIAO. Research Progress on Mechanism of Baicalin in Preventing and Treating Diabetic Nephropathy[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (4) : 24 -27 . DOI: 10.13193/j.issn.1673-7717.2026.04.006
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Year 2026 volume 44 Issue 4
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doi: 10.13193/j.issn.1673-7717.2026.04.006
  • Online Date：2026-10-14
  • Published：2026-04-10
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    School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, Guangdong, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
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Genus		 种数
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Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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