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Outline
To investigate the effect of Compound Danshen Dripping Pills（复方丹参滴丸）combined with edaravone and dexborneol concentrated solution on serum amyloid in the patients with acute cerebral infarction.
One hundred and fifty inpatients with acute cerebral infarction in the Neurology Department of Tangshan Gongren Hospital from January 2022 to January 2024 were selected and grouped according to different treatment methods. All participants were given butylphthalide treatment. Based on this, the control group（74 cases）was given edaravone and dexborneol concentrated solution, whereas the observation group（76 cases）added Compound Danshen Dripping Pills combined with edaravone and dexborneol concentrated solution. The treatment in both groups lasted for 10-14 d. Then the neurological function recovery, serum amyloid, glycated serum protein, retinol binding protein 4, hemorheological parameters, clinical efficacy and adverse reactions were compared between two groups.
The observation group reported a lower score on National Institutes of Health Stroke Scale and modified Rankin Scale, and a higher Barthel index compared to the control group（P<0.05）. The levels of serum amyloid, glycated serum protein and retinol binding protein 4 decreased in the observation group compared to those in the control group（P<0.05）. The high and low shear whole blood viscosities, plasma viscosity and hematocrit were all smaller in the observation group than those in the control group（P<0.05）. The observation group denoted a higher overall efficacy rate than the control group（P<0.05）, while no statistical difference was found in adverse reaction rate between two groups（P>0.05）.
The application of Compound Danshen Dripping Pills combined with edaravone and dexborneol concentrated solution in patients with acute cerebral infarction can effectively promote the recovery of neurological function, reduce the levels of serum amyloid, glycated serum protein and retinol binding protein 4, and ameliorate the blood viscosity.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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