To investigate the effect of Modified Tiaochong Decoction (调冲汤加减) in the treatment of infertility of kidney deficiency and liver depression and its effect on hormone levels of the patients.

From January 2023 to January 2024, 98 cases of infertility patients with kidney deficiency and liver stagnation were selected and simply randomized into groups, with 49 cases in each group. The control group was given conventional western medicine clomiphene, and the observation group was given Tiaochong Decoction combined with conventional western medicine. The clinical efficacy, traditional Chinese medicine (TCM) syndrome scores, hormone levels［follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T) ］, maximum follicle diameter, endometrial thickness, ovulation rate and pregnancy rate of two groups were compared.

The total effective rate of treatment in the observation group was 95.92% (47/49), higher than that in the control group［81.63% (40/49) ］ (P<0.05) . After treatment, the symptoms scores of TCMin the observation group were lower (P<0.05) . At the end of the treatment and 6 months after treatment, the serum levels of FSH, LH and T in the observation group were lower (P<0.05) . The maximum follicular diameter and endometrial thickness of the observation group at the end of treatment and 6 months after treatment were higher than those of the control group (P<0.05). The ovulation rate and pregnancy rate in the observation group were higher (P<0.05) .

The combination of Modified Tiaochong Decoction combined with conventional western medicine can improve the uterine physiological function and the treatment effect by regulating hormone secretion, relieve the clinical signs of the infertility patients with kidney deficiency and liver depression, and increase the pregnancy rate.