To observe the curative effect of Shunao Jieyu Decoction(疏脑解郁汤)combined with moxibustion of regulating governor and relieving depression-transcranial magnetic stimulation(rTMS)on the rehabilitation of the patients with post-stroke depression(PSD).
A total of PSD patients admitted to Hebei Provincial Hospital of Traditional Chinese Medicine from June 2021 to January 2023 were randomly divided into the combined group(60 cases)and the control group(60 cases). Both groups were treated with Escitalopram Oxalate Tablets and the moxibustion method of regulating Du meridian and relieving depression-rTMS, and the combined group was intervened with Shunao Jieyu Decoction for 4 weeks. The changes of Hamilton Depression Scale(HAMD), TCMsyndrome scores and modified Edinburgh-Scandinavian stroke scale(MESSS)before and after treatment were compared between the two groups. The side effects of the two groups were evaluated by Asperger's anti-depressant side effects scale, and the therapeutic effects of the two groups were evaluated after treatment.
After 2 and 4 weeks of treatment, the HAMD scores, TCMsyndrome scores and MESSS scale scores of the two groups decreased compared with those before treatment, while the scores of the combined group were lower than those of the control group after 2 and 4 weeks of treatment(P<0.05). The incidence of side effects in the combined group and the control group were 15.00%(9/60)and 18.33%(11/60), respectively, and there was no statistical difference between the two groups(P>0.05). The total effective rate of the combined group was 91.67%(55/60), which was significantly higher than that of the control group(76.67%, 46/60)(P<0.05).
On the basis of regulating Du and relieving depression moxibustion-rTMS therapy, the combined application of Shunao Jieyu Decoction can effectively regulate the depression, relieve the clinical symptoms and improve the neurological function without affecting the safety of treatment, so as to achieve a more ideal therapeutic effect.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |