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Quality Control Status and Predictive Analysis of Quality Markers of Qiancao (Rubiae Radix et Rhizoma)
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Xiaoyan ZHANG1, Ziyao QIAO2, Kairu DING2, Kaihua LONG1, Tingting SUN1, Hong ZHANG1, 2, Ye LI1, 2, Yang LIU1, 2
Chinese Archives of Traditional Chinese Medicine | 2026, 44(6) : 209 - 214
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(6): 209-214
• Platform of Provincial Project •
Quality Control Status and Predictive Analysis of Quality Markers of Qiancao (Rubiae Radix et Rhizoma)
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Xiaoyan ZHANG1, Ziyao QIAO2, Kairu DING2, Kaihua LONG1, Tingting SUN1, Hong ZHANG1, 2, Ye LI1, 2, Yang LIU1, 2
Affiliations
  • 1.Shaanxi Academy of Traditional Chinese Medicine, Xi'an 710003, Shaanxi, China
  • 2.College of Life Science, Northwest University, Xi'an 710069, Shaanxi, China
Published: 2026-06-10 doi: 10.13193/j.issn.1673-7717.2026.06.039
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Qiancao (Rubiae Radix et Rhizoma) contains active ingredients such as quinones, cyclopeptides, terpenes and polysaccharides, which have the effects of promoting blood circulation, removing blood stasis, stopping bleeding and dredging meridians. It is widely used in traditional Chinese medicine clinical practice. However, there are problems with adulteration, excessive nonmedicinal parts and substandard content in Qiancao (Rubiae Radix et Rhizoma) currently, and the existing quality control indicators make it difficult to evaluate the quality of medicinal materials comprehensively. Based on research progress on quality control of Qiancao (Rubiae Radix et Rhizoma), its quality markers were predicted and analyzed from 7 aspects such as plant genetic relationship, traditional efficacy, different origins, compatibility of different compounds, new pharmacodynamic pathway and measurable chemical compounds. The results suggested that alizarin, purpurin, 6-hdroxyrubiadin, xnthopurpurin, rbiadin, mollugin, rbioncolin C, xyloidone, lpachol, isolariciresinol, RA-Ⅴ, RA-Ⅶ and β-sitosterol can be used as quality markers of Qiancao (Rubiae Radix et Rhizoma), providing a reference for its quality standard improvement and other research in the future.

Qiancao (Rubiae Radix et Rhizoma)  /  quality control  /  quality markers  /  quinones  /  Rubiaceae-type cyclopeptides
张笑颜, 乔子尧, 丁凯茹, 龙凯花, 孙婷婷, 张红, 李晔, 刘洋. 茜草质量控制研究进展及质量标志物（Q-Marker）预测. 中华中医药学刊, 2026 , 44 (6) : 209 -214 . DOI: 10.13193/j.issn.1673-7717.2026.06.039
Xiaoyan ZHANG, Ziyao QIAO, Kairu DING, Kaihua LONG, Tingting SUN, Hong ZHANG, Ye LI, Yang LIU. Quality Control Status and Predictive Analysis of Quality Markers of Qiancao (Rubiae Radix et Rhizoma)[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (6) : 209 -214 . DOI: 10.13193/j.issn.1673-7717.2026.06.039
Appendix
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Year 2026 volume 44 Issue 6
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doi: 10.13193/j.issn.1673-7717.2026.06.039
  • Online Date：2026-10-14
  • Published：2026-06-10
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    1.Shaanxi Academy of Traditional Chinese Medicine, Xi'an 710003, Shaanxi, China
    2.College of Life Science, Northwest University, Xi'an 710069, Shaanxi, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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