To analyze the effects of Modified Buyang Huanwu Decoction（补阳还五汤加减）combined with consciousness-restoring and orifice-opening acupuncture on hemorheology and serum levels of interleukin-6（IL-6）and tumor necrosis factor-α（TNF-α） in patients with ischemic stroke in the convalescent period（Qi deficiency syndrome）.

From April 2022 to March 2024, 80 patients with ischemic stroke in the convalescent period who were admitted to rehabilitation medicine department of the hospital were selected and divided into the control group（4 weeks of conventional treatment with Modified Buyang Huanwu Decoction）and the observation group（4 weeks of combined treatment with Modified Buyang Huanwu Decoction and consciousness-restoring and orifice-opening acupuncture）using the random number table method, with 40 cases in each group. The TCMclinical effect, hemorheology[whole blood high-shear viscosity, whole blood low-shear viscosity, plasma viscosity and fibrinogen（FIB）], neurological function indicators[the National Institutes of Health Stroke Scale（NIHSS）, nerve growth factor（NGF）and brain-derived neurotrophic factor（BDNF）], serum levels of IL-6 and TNF-α, quality of life[Short Form 36（SF-36）]and the incidence of adverse reactions were compared between the groups.

The effective rate of treatment in the observation group（92.50%, 37/40）was higher than that in the control group（75.00%, 30/40）（P<0.05）. After treatment, the levels of whole blood high-shear viscosity, whole blood low-shear viscosity, plasma viscosity and FIB in the observation group were lower than those in the control group（P<0.05）. After treatment, NIHSS score of the observation group was lower than that of the control group, and the levels of NGF and BDNF were higher than those of the control group（P<0.05）. The serum levels of IL-6 and TNF-αin the observation group after 2 and 4 weeks of treatment were lower than those in the control group, while SF-36 scores were higher than those of the control group（P<0.05）. The incidence rates of adverse reactions in the two groups were 12.50%（5/40）and 10.00%（4/40）, without statistically significant difference between two groups（P>0.05）.

Applying Modified Buyang Huanwu Decoction combined with consciousness-restoring and orifice-opening acupuncture in the treatment of patients with Qi deficiency type of ischemic stroke in the convalescent period can significantly improve the clinical effect, hemorheology, serum levels of IL-6 and TNF-α, neurological function and quality of life. It is safe and reliable.