To observe the effect of acupuncture combined with Chaihu Shugan Powder (柴胡疏肝散) and five-tone therapy in the patients with breast hyperplasia of liver depression and Qi stagnation type.
Eighty patients with hyperplasia of mammary glands of liver depression and Qi stagnation type diagnosed and treated in the hospital from April 2021 to December 2023 were selected as the research objects. They were randomly divided into two groups. Forty patients in the control group were treated with Chaihu Shugan Powder and five-tone therapy. Forty patients in the observation group were treated with acupuncture on the basis of the control group. The treatment cycle was 2 months. The clinical efficacy, breast mass indexes (mass texture, mass range, mass size), sex hormone index[estradiol (E2), progesterone (P), prolactin (PRL) ]and adverse reactions were compared between the two groups.
The markedly effective rate of the observation group was 85.00% (34/40), which was significantly higher than 65.00% (26/40) of the control group (P<0.05) . After treatment, the corresponding scores of tumor grade, tumor range and tumor size in the two groups were significantly decreased, and those in the observation group were lower than those in the control group[ (2.46±0.74) points, (3.11±0.89) points, (3.34±0.43) points vs (2.92±0.65) points, (6.07±1.58) points, (3.90±0.37) points] (P<0.05) . After treatment, the levels of serum E2 and PRL decreased and the level of P increased in both groups. The levels of serum E2 and PRL in the observation group were lower than those in the control group, and the level of P was higher than that in the control group[ (64.82±6.31) pg/mL, (0.81±0.17) ng/mL, (16.78±2.49) ng/mL vs (69.53±7.06) pg/mL, (0.69±0.22) ng/mL, (19.05±3.14) ng/mL] (P<0.05) . No serious adverse reactions occurred in the two groups.
Acupuncture combined with Chaihu Shugan Powder and five-tone therapy has a significant effect on hyperplasia of mammary glands with liver depression and Qi stagnation. It can effectively improve the patients'ultrasound imaging and sex hormone indicators, and has a positive impact.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |