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Outline
Yinchen Wuling Powder (茵陈五苓散, YWP) has the efficacy of clearing heat, detoxicating and inducing dampness, strengthening spleen and stomach, and resolving turbidity. Modern studies have shown that this formula has the hepatoprotective, choleretic, cardiovascular protection and anti-inflammatory effects. It is commonly used in the treatment of jaundice, metabolic diseases and cardiovascular diseases in clinical practice. In this paper, it systematically summarized and sorted out the chemical composition and pharmacological effects of YWP, and carried out the prediction analysis of its quality markers (Q-Markers) according to the concept of Q-Markers based on the five principles, and the results showed that chlorogenic acid, artemisinin lactone, chromogenic ketone, swertiamarin bitter glycoside, 3, 5-O-dicaffeoylquinic acid, 4, 5-O-di caffeoylquinic acid, atractylenolide Ⅰ, atractylenolide Ⅱ, atractylenolide Ⅲ, atractylenolide, craniospermone, cinnamic acid, cinnamaldehyde, porinic acid, tuliptic acid, dehydrotuliptic acid, 2, 3-acetylzelenol B, 2, 3-acetylzelenol C, zeylenol B and ergosterol could be used as the Q-Markers of YWP, which would be used as a reference for the subsequent studies of the quality control of YWP and its related formulations.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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