To observe the clinical effect and safety of Chaipo Decoction（柴朴汤）combined with Sulidi in the treatment of bronchial asthma.

A total of 92 patients with bronchial asthma admitted from March 2022 to March 2024 were included in this study.The patients were divided into two groups by random number table method，namely，the Sulidiere group receiving Sulidiere treatment and the Chaipo Decoction group receiving Sulidiere treatment combined with Chaipo Decoction，with 46 cases in each group.The patient data of each group was observed，including the clinical efficacy，adverse reactions and TCM symptom score before and after treatment（sleeping at night and waking up in the morning with severe cough，dry cough with little or no phlegm，rib distension，restlessness and chest tightness，and discomfort in the throat，etc.）and sputum inflammatory factor index changes，pulmonary function index and index of immune function changes，asthma control test（ACT）and Mini Asthma Quality of Life Questionnaire（Mini AQLQ）.

The total effective rate of the Chaipo Decoction group was higher than that of the Sulidiere group（P<0.05）.The adverse reaction rate of patients in Chaipo Decoction group was similar to that in Sulidiere group（P>0.05）.Before treatment，the patients in both groups received traditional Chinese medicine syndrome scores（sleeping at night and waking up in themorning with severe cough，dry cough with little or no phlegm，rib distension，restlessness and chest tightness，and discomfort in the throat，etc.），interleuin 6（IL-6），interleuin 17（IL-17），tumour necrosis factor-α（TNF-α）and other indicators of sputum factors，forced vital capacity（FVC）and forced expiratory volume in one second（FEV1），percentage of forced expiratory volume at the first second to forced vital capacity（FEV1%）and other pulmonary function indicators，CD3⁺，CD4⁺，CD8⁺，CD4⁺/CD8⁺and other immune function indicators，ACT and Mini AQLQ scores were not significant（P>0.05）.After treatment，TCM syndrome scores（coughing up atnight and in the morning，dry cough with little or no sputum，hypochthmic fullness，upset chest tightness，pharyngeal distress，etc.），sputum inflammatory factor indexes（IL-6，IL-17，TNF-α），lung function indexes（FVC，FEV1，FEV1%），and immune function indexes（CD3⁺，CD4⁺，CD8⁺，CD4⁺/CD8⁺）of all patients in each group，ACT and Mini AQLQ scores were improved.After treatment，patients in the Chaipo Decoction group had TCM syndrome scores（sleeping at night and waking up in the morning with severe cough，dry cough with little or no phlegm，rib distension，restlessness and chest tightness，and discomfort in the throat，etc.），sputum inflammatory factor indexes（IL-6，IL-17，TNF-α），lung function indexes（FVC，FEV1，FEV1%）and immune function indexes（CD3⁺，CD4⁺，CD8⁺，CD4⁺/CD8⁺），ACT and Mini AQLQ scores were better than those in the Seridial group（P<0.05）.

The clinical effect of Chaipo Decoction combined with Sulidi in the treatment of bronchial asthma is good.The inflammation of the patients is significantly improved.The symptoms and lung function are improved.The disease is controlled.The quality of life is improved.The adverse reactions are less.The treatment is relatively safe and reliable.