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Research Progress on Mechanism of Huanglian(Coptidis Rhizoma)and Its Active Ingredients in Treating Gastric Ulcers
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Liming CHEN1, Guozheng LIU2, Hui WANG3, Yan LI1, Yangyang SUN1, Yilin ZHAO1, Jingdong XIAO3
Chinese Archives of Traditional Chinese Medicine | 2025, 43(12) : 33 - 41
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Chinese Archives of Traditional Chinese Medicine | 2025, 43(12): 33-41
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Research Progress on Mechanism of Huanglian(Coptidis Rhizoma)and Its Active Ingredients in Treating Gastric Ulcers
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Liming CHEN1, Guozheng LIU2, Hui WANG3, Yan LI1, Yangyang SUN1, Yilin ZHAO1, Jingdong XIAO3
Affiliations
  • 1.Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China
  • 2.The Fourth Affiliated Hospital of Liaoning University of Traditional Chinese Medicine Hospital,Shenyang 110101,Liaoning,China
  • 3.The First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China
Published: 2025-12-10 doi: 10.13193/j.issn.1673-7717.2025.12.006
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Gastric ulcer is a common clinical gastrointestinal disease,which is characterized by its susceptibility,recurrence and high medical cost.Nowadays,due to the extensive use of proton pump inhibitors,H2 receptor antagonists and antimicrobial drugs,the incidence of gastric ulcers has decreased,but the recurrence rate of gastric ulcers and the incidence of complications are still not effectively controlled.The Chinese herb Huanglian(Coptidis Rhizoma)has the effects of clearing heat and drying dampness,purging fire and removing toxin,which plays a significant role in the treatment of sores,carbuncles and ulcers,and it can enter the stomach meridian,which iswidely used in the treatment of gastric ulcers,and it can effectively reduce the index of ulcers and accelerate the healing of ulcers.Through searching CNKI,Pubmed and other databases,the article comprehensively discussed the mechanism of Huanglian(Coptidis Rhizoma)and its active ingredients in the treatment of gastric ulcers,in order to provide a basis for the clinical application of Huanglian(Coptidis Rhizoma)in ulcer diseases as well as further scientific research.

Huanglian(Coptidis Rhizoma)  /  gastric ulcer  /  berberine  /  mechanism of action  /  clearing heat and removing toxin
Liming CHEN, Guozheng LIU, Hui WANG, Yan LI, Yangyang SUN, Yilin ZHAO, Jingdong XIAO. Research Progress on Mechanism of Huanglian(Coptidis Rhizoma)and Its Active Ingredients in Treating Gastric Ulcers[J]. Chinese Archives of Traditional Chinese Medicine, 2025 , 43 (12) : 33 -41 . DOI: 10.13193/j.issn.1673-7717.2025.12.006
Year 2025 volume 43 Issue 12
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doi: 10.13193/j.issn.1673-7717.2025.12.006
  • Online Date:2026-04-29
  • Published:2025-12-10
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    1.Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China
    2.The Fourth Affiliated Hospital of Liaoning University of Traditional Chinese Medicine Hospital,Shenyang 110101,Liaoning,China
    3.The First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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