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Research Advances and Quality Marker Analysis of Danggui Shaoyao Powder (当归芍药散) in Treatment of Gynecological Diseases
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Yuhe WU1, 2, Lyuyuan LIANG3, 4, Jialei CAO3, 4, Mengke PEI1, 2, Huijuan WANG1, 2, Xiaoyu NIU1, 2, Yiwen KONG1, 2, Bingqi WEI5, Yanli SONG1, 2, Bingxiang MA3, 4
Chinese Archives of Traditional Chinese Medicine | 2026, 44(9) : 194 - 201
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(9): 194-201
• Target on National Project •
Research Advances and Quality Marker Analysis of Danggui Shaoyao Powder (当归芍药散) in Treatment of Gynecological Diseases
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Yuhe WU1, 2, Lyuyuan LIANG3, 4, Jialei CAO3, 4, Mengke PEI1, 2, Huijuan WANG1, 2, Xiaoyu NIU1, 2, Yiwen KONG1, 2, Bingqi WEI5, Yanli SONG1, 2, Bingxiang MA3, 4
Affiliations
  • 1.The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou 450000, Henan, China
  • 2.First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
  • 3.School of Pediatrics, Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
  • 4.Henan Suchen Health Technology Co., Ltd., Zhengzhou 450000, Henan, China
  • 5.Henan Provincial Hospital of Traditional Chinese Medicine, Zhengzhou 450000, Henan, China
Published: 2026-09-10 doi: 10.13193/j.issn.1673-7717.2026.09.035
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Danggui Shaoyao Powder (当归芍药散), originating from ZHANG Zhongjing's Jingui Yaolue in the Eastern Han Dynasty, is renowned for its efficacy in nourishing blood, regulating menstruation and promoting blood circulation to remove stasis. The formula comprises complex chemical components, primarily including phenolic acids, glycosides, polysaccharides and volatile oils. Modern pharmacological studies have demonstrated that Danggui Shaoyao Powder exhibits anti-inflammatory, antioxidant, immunomodulatory, microcirculation-improving and endocrine-regulating effects. It is widely used in clinical practice for gynecological disorders such as menstrual irregularities, dysmenorrhea, postpartum abdominal pain, chronic pelvic inflammatory disease and endometriosis. Based on the “five principles” of quality markers, the potential quality markers for Danggui Shaoyao Powder may include paeoniflorin, ferulic acid, 23-acetylalisol B, 23-acetylalisol C, atractylenolide Ⅲ, atractylenolide Ⅰ, pachymic acid, kaempferol and β-sitosterol. Future research should further focus on its active components and mechanisms of action, providing a scientific basis for the modern development and quality evaluation system of Danggui Shaoyao Powder.

Danggui Shaoyao Powder (当归芍药散)  /  chemical components  /  pharmacological effects  /  clinical applications  /  quality markers
兀玉荷, 梁绿圆, 曹佳蕾, 裴梦珂, 王会娟, 牛啸宇, 孔奕文, 魏炳琦, 宋艳丽, 马丙祥. 当归芍药散治疗妇科疾病的研究进展及质量标志物分析. 中华中医药学刊, 2026 , 44 (9) : 194 -201 . DOI: 10.13193/j.issn.1673-7717.2026.09.035
Yuhe WU, Lyuyuan LIANG, Jialei CAO, Mengke PEI, Huijuan WANG, Xiaoyu NIU, Yiwen KONG, Bingqi WEI, Yanli SONG, Bingxiang MA. Research Advances and Quality Marker Analysis of Danggui Shaoyao Powder (当归芍药散) in Treatment of Gynecological Diseases[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (9) : 194 -201 . DOI: 10.13193/j.issn.1673-7717.2026.09.035
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Year 2026 volume 44 Issue 9
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doi: 10.13193/j.issn.1673-7717.2026.09.035
  • Online Date：2026-10-20
  • Published：2026-09-10
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Affiliations
    1.The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou 450000, Henan, China
    2.First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
    3.School of Pediatrics, Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
    4.Henan Suchen Health Technology Co., Ltd., Zhengzhou 450000, Henan, China
    5.Henan Provincial Hospital of Traditional Chinese Medicine, Zhengzhou 450000, Henan, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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