Full
Outline
To analyze the therapeutic effect of acupuncture therapy and high-frequency repetitive transcranial magnetic stimulation (rTMS) on neuropathic pain of spinal cord injury.
A total of 92 patients with spinal cord injury-induced neuropathic pain treated at the Spinal Cord Rehabilitation Department of Xi'an International Medical Center Hospital from June 2021 to May 2024, were enrolled in this study. The patients were randomly divided into two groups using a random number table method. The control group (46 cases) received high-frequency rTMS treatment, while the observation group (46 cases) received a combination of acupuncture therapy and high-frequency rTMS. The two groups were compared in terms of treatment efficacy, pain levels, neuroelectrophysiological parameters, oxidative stress markers, serum inflammatory cytokine levels and psychological status scores.
The total effective rate of the observation group was 93.48%, which was much higher than that of the control group (76.09%), and the difference between groups was significant (P<0.05). The visual analogue scale (VAS) score of the observation group was lower than that of the control group 1, 2 and 3 months after treatment (P<0.05). After treatment, American Spinal Injury Association (ASIA) sensory and motor scores, resting motor threshold (RMT) and motor evoked potential (MEP) in the observation group were higher than those in the control group (P<0.05). After treatment, the levels of tumor necrosis factor-α (TNF-α), interleukin-10 (IL-10) and interleukin-6 (IL-6) in the observation group were lower than those in the control group (P<0.05). After treatment, the Hamilton Depression Rating Scale (HAMD) and Hamilton Anxiety Rating Scale (HAMA) scores of the observation group were lower than those of the control group (P<0.05).
In summary, acupuncture therapy combined with high-frequency rTMS can effectively reduce the degree of pain in the patients with neuropathic pain from spinal cord injury, regulate the serum inflammatory factors and oxidative stress response, play a protective role on nerves, and promote the recovery of nerve function.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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