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Research Progress on Chemical Constituents Pharmacological Effects and Clinical Applications of Jiegeng Decoction (桔梗汤) and Predictive Analysis of Its Quality Marker
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Jie WANG1, Qili ZHANG2, Peng TIAN3, Jianghong MA1, Xiaoyu GAO1, Xia PAN1, Lei ZHAO2
Chinese Archives of Traditional Chinese Medicine | 2026, 44(8) : 53 - 57
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(8): 53-57
• Target on National Project •
Research Progress on Chemical Constituents Pharmacological Effects and Clinical Applications of Jiegeng Decoction (桔梗汤) and Predictive Analysis of Its Quality Marker
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Jie WANG1, Qili ZHANG2, Peng TIAN3, Jianghong MA1, Xiaoyu GAO1, Xia PAN1, Lei ZHAO2
Affiliations
  • 1.Dinxi Pharmaceutical Inspection and Testing Center, Dinxi 743000, Gansu, China
  • 2.Gansu University of Chinese Medicine, Gansu Provincial Key Laboratory of Chemistry and Quality Research of Chinese and Tibetan Medicine, Gansu Provincial Engineering Laboratory of Quality Standardization Technology Research and Promotion of Authentic Medicinal, Lanzhou 730050, Gansu, China
  • 3.940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050, Gansu, China
Published: 2026-08-10 doi: 10.13193/j.issn.1673-7717.2026.08.012
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Jiegeng Decoction (桔梗汤) comes from ZHANG Zhongjing's Synopsis of the Golden Chamber in the Han Dynasty. Jiegeng Decoction belongs to lung meridian. It is a channeling medicine for lung. It has the function of ventilating lung and promoting throat, expelling phlegm and discharging pus. Jiegeng Decoction is a classic prescription for treating cough and sore throat. Pharmacological studies have shown that Jiegeng Decoction has reliving cough, dispelling phlegm, anti-inflammation and protecting liver effects. The clinical research is mainly used to treat common diseases of respiratory system, ear-nose-throat system, digestive system and urinary system. On the basis of summarizing the research progress of chemical composition, pharmacological action and clinical application of Jiegeng Decoction, according to the “five principles” of quality marker (Q-Marker), in other words, quality transfer and traceability, component specificity, component and pharmacodynamic correlation, component measurability and compound compatibility environment were analyzed to predict Q-Markers of Jiegeng Decoction. The results showed that glycyrrhizic acid, Platycodin D, glycyrrhizin, glycyrrhetinic acid and glycyrrhetin A could be used as Q-Markers of Jiegeng Decoction to provide reference for the quality control of Jiegeng Decoction and its related preparations.

Jiegeng Decoction (桔梗汤)  /  chemical composition  /  pharmacological action  /  clinical application  /  quality markers
汪洁, 张启立, 田鹏, 马江红, 高晓昱, 潘遐, 赵磊. 经典名方桔梗汤化学成分、药理作用、临床应用研究进展及Q-Marker预测分析. 中华中医药学刊, 2026 , 44 (8) : 53 -57 . DOI: 10.13193/j.issn.1673-7717.2026.08.012
Jie WANG, Qili ZHANG, Peng TIAN, Jianghong MA, Xiaoyu GAO, Xia PAN, Lei ZHAO. Research Progress on Chemical Constituents Pharmacological Effects and Clinical Applications of Jiegeng Decoction (桔梗汤) and Predictive Analysis of Its Quality Marker[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (8) : 53 -57 . DOI: 10.13193/j.issn.1673-7717.2026.08.012
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Year 2026 volume 44 Issue 8
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doi: 10.13193/j.issn.1673-7717.2026.08.012
  • Online Date：2026-10-20
  • Published：2026-08-10
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    1.Dinxi Pharmaceutical Inspection and Testing Center, Dinxi 743000, Gansu, China
    2.Gansu University of Chinese Medicine, Gansu Provincial Key Laboratory of Chemistry and Quality Research of Chinese and Tibetan Medicine, Gansu Provincial Engineering Laboratory of Quality Standardization Technology Research and Promotion of Authentic Medicinal, Lanzhou 730050, Gansu, China
    3.940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou 730050, Gansu, China
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表12种不同金属材料的力学参数
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Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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