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Outline
Baitouweng Decoction (白头翁汤) is extracted from Treatise on Febrile Diseases, with the effect of clearing heat and removing toxin, cooling blood and stopping dysentery, which is specific for Jueyin heat dysentery. Modern studies showed that PD has the pharmacological action of anti-inflammation, anti-bacteria and anti-cancer, and is widely used in digestive system diseases such as ulcerative colitis, radiation enteritis and colorectal cancer. This study adopted the bibliometric method. Based on ancient book databases such as the Chinese Medical Canon and the China National Knowledge Infrastructure (CNKI) database, relevant literatures of PD were retrieved. The key information such as the historical evolution, prescription meaning and composition, prescription dosage, decoction and preparation methods, drug origin and modern clinical application of this prescription were investigated and verified. Referring to the “five principles” of quality markers (Q-Markers), the quality markers of PD were predicted. The results indicated that PD had a constant inheritance throughout the ages, clear drug origin and definite efficacy and indications. The dosage conversion should be carried out according to the weights and measures of the Han Dynasty. It is found that the active ingredients such as anemoside B4, berberine and epiberberine could be used as the potential quality markers of PD, providing a basis for expanding the clinical application of this formula and the development and application of compound preparations.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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