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Research Progress of Modern Clinical Application and Mechanism of Action of Huanglian Wendan Decoction (黄连温胆汤)
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Jiayi GUAN1, Mingliang QIAO2, Chenyi ZHAO2, Peiyuan ZHAO3, Fangrui YIN1, Yi MENG2
Chinese Archives of Traditional Chinese Medicine | 2026, 44(7) : 141 - 147
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(7): 141-147
• Target on National Project •
Research Progress of Modern Clinical Application and Mechanism of Action of Huanglian Wendan Decoction (黄连温胆汤)
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Jiayi GUAN1, Mingliang QIAO2, Chenyi ZHAO2, Peiyuan ZHAO3, Fangrui YIN1, Yi MENG2
Affiliations
  • 1.The Second Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou 450003, Henan, China
  • 2.Henan Provincial Hospital of Traditional Chinese Medicine, Zhengzhou 450003, Henan, China
  • 3.Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
Published: 2026-07-10 doi: 10.13193/j.issn.1673-7717.2026.07.026
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Huanglian Wendan Decoction (黄连温胆汤) is derived from LU Tingzhen's Six Causes of Differentiation. It has the effect of clearing heat and drying dampness, regulating Qi and eliminating phlegm, and is often used in the treatment of phlegm heat syndrome. Huanglian Wendan Decoction is widely used in clinical practice, and can be used in diseases of nervous system, digestive system, cardiovascular system, respiratory system, endocrine system, urinary system and pediatrics. In terms of basic research, its mechanism of action is related to inhibiting inflammation, regulating glucose and lipid metabolism, improving insulin resistance, regulating neurotransmitters, regulating intestinal flora, anti-oxidative stress, protecting vascular endothelial cells and growth factors, anti-atherosclerosis, protecting liver and kidney tissue, inhibiting apoptosis, etc. By summarizing relevant literatures in recent years, this paper summarized the clinical application and mechanism of Huanglian Wendan Decoction, in order to provide a basis for the further application of Huanglian Wendan Decoction and promote the in-depth exploration and discussion of Huanglian Wendan Decoction.

Huanglian Wendan Decoction (黄连温胆汤)  /  clinical application  /  mechanism of action  /  review
关佳怡, 乔明亮, 赵晨怡, 赵培源, 尹芳蕊, 孟毅. 黄连温胆汤现代临床应用及作用机制研究进展. 中华中医药学刊, 2026 , 44 (7) : 141 -147 . DOI: 10.13193/j.issn.1673-7717.2026.07.026
Jiayi GUAN, Mingliang QIAO, Chenyi ZHAO, Peiyuan ZHAO, Fangrui YIN, Yi MENG. Research Progress of Modern Clinical Application and Mechanism of Action of Huanglian Wendan Decoction (黄连温胆汤)[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (7) : 141 -147 . DOI: 10.13193/j.issn.1673-7717.2026.07.026
Year 2026 volume 44 Issue 7
88
14
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doi: 10.13193/j.issn.1673-7717.2026.07.026
  • Online Date:2026-10-20
  • Published:2026-07-10
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    1.The Second Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou 450003, Henan, China
    2.Henan Provincial Hospital of Traditional Chinese Medicine, Zhengzhou 450003, Henan, China
    3.Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
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属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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