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Research Progress of Xiaoyao Powder (逍遥散) in Treatment of Depression
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Yiting HUANG1, 2, Ningfang MO1, 2, Qiuyun QIN1, 2, Niuniu LI1, 2, Meng XIA1, 2
Chinese Archives of Traditional Chinese Medicine | 2026, 44(7) : 98 - 104
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(7): 98-104
• Target on National Project •
Research Progress of Xiaoyao Powder (逍遥散) in Treatment of Depression
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Yiting HUANG1, 2, Ningfang MO1, 2, Qiuyun QIN1, 2, Niuniu LI1, 2, Meng XIA1, 2
Affiliations
  • 1.Guangxi University of Chinese Medicine, Nanning 530200, Guangxi, China
  • 2.Key Laboratory of Liver and Spleen Viscera of Guangxi Traditional Chinese Medicine, Nanning 530200, Guangxi, China
Published: 2026-07-10 doi: 10.13193/j.issn.1673-7717.2026.07.019
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Depression is a serious emotional mental disorder that poses a major threat to human health. This study elucidated the pathogenesis of depression from the perspective of traditional Chinese medicine, explored the rationale for the prescription of Xiaoyao Powder (逍遥散) and its pharmacodynamic foundation in treating depression, and examined the therapeutic mechanisms of Xiaoyao Powder through five dimensions: modulation of neurotransmitters, regulating cytokines and inflammatory reactions, regulating signaling pathways, regulating hypothalamic-pituitary-adrenal (HPA) axis and reducing hippocampal neuron damage. This manuscript aimed to offer valuable theoretical insights for the clinical utilization and further investigation of Xiaoyao Powder.

Xiaoyao Powder (逍遥散)  /  depression  /  neurotransmitters  /  inflammatory reaction  /  signal pathway  /  HPA axis
黄依婷, 磨宁芳, 秦秋云, 李妞妞, 夏猛. 逍遥散治疗抑郁症的研究进展. 中华中医药学刊, 2026 , 44 (7) : 98 -104 . DOI: 10.13193/j.issn.1673-7717.2026.07.019
Yiting HUANG, Ningfang MO, Qiuyun QIN, Niuniu LI, Meng XIA. Research Progress of Xiaoyao Powder (逍遥散) in Treatment of Depression[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (7) : 98 -104 . DOI: 10.13193/j.issn.1673-7717.2026.07.019
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Year 2026 volume 44 Issue 7
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doi: 10.13193/j.issn.1673-7717.2026.07.019
  • Online Date：2026-10-20
  • Published：2026-07-10
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    1.Guangxi University of Chinese Medicine, Nanning 530200, Guangxi, China
    2.Key Laboratory of Liver and Spleen Viscera of Guangxi Traditional Chinese Medicine, Nanning 530200, Guangxi, China
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