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Research Progress and Development Thinking on Anti-Tumor Mechanism of Bajiaolian (Dysosma versipellis)
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Yan LEI1, Zhangtian TANG1, Yanhong WANG2, Ding LI3, Xianbin KONG4, Chuanxin LIU5, Hongyan JIA1
Chinese Archives of Traditional Chinese Medicine | 2026, 44(7) : 79 - 85
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(7): 79-85
• Target on National Project •
Research Progress and Development Thinking on Anti-Tumor Mechanism of Bajiaolian (Dysosma versipellis)
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Yan LEI1, Zhangtian TANG1, Yanhong WANG2, Ding LI3, Xianbin KONG4, Chuanxin LIU5, Hongyan JIA1
Affiliations
  • 1.The First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China
  • 2.Department of Microbiology and Immunology, Shanxi Medical University, Taiyuan 030001, Shanxi, China
  • 3.The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, Henan, China
  • 4.College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
  • 5.Henan Key Laboratory of Rare Diseases, Endocrinology and Metabolism Center, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang 471003, Henan, China
Published: 2026-07-10 doi: 10.13193/j.issn.1673-7717.2026.07.016
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In recent years, Bajiaolian (Dysosma versipellis), a traditional Chinese medicine, has emerged as a significant focus in anti-tumor research due to its distinctive toxicological and pharmacological properties. Evidence from various studies indicates that Bajiaolian (Dysosma versipellis) and its active constituents possess the ability to inhibit the development of multiple cancer types, including breast, lung, colorectal, liver and gastric cancers. The proposed mechanisms of action primarily involve the suppression of tumor cell proliferation, invasion and migration, the induction of apoptosis in tumor cells, and the disruption of the tumor cell cycle. These attributes suggest that Bajiaolian (Dysosma versipellis) holds considerable promise for application in anti-tumor therapy. This review aimed to elucidate the anti-tumor effects and underlying mechanisms of Bajiaolian (Dysosma versipellis) and its active components, thereby providing a theoretical foundation for the future medicinal development of Bajiaolian (Dysosma versipellis) and contributing novel insights and directions for the research and innovation of anti-tumor agents.

Bajiaolian (Dysosma versipellis)  /  anti-tumor  /  podophyllotoxin  /  mechanism of action  /  constitution-based toxicology  /  toxicological evidence chain
雷艳, 唐张甜, 王艳红, 李丁, 孔宪斌, 刘传鑫, 贾红燕. 八角莲抗肿瘤作用的研究进展及发展思考. 中华中医药学刊, 2026 , 44 (7) : 79 -85 . DOI: 10.13193/j.issn.1673-7717.2026.07.016
Yan LEI, Zhangtian TANG, Yanhong WANG, Ding LI, Xianbin KONG, Chuanxin LIU, Hongyan JIA. Research Progress and Development Thinking on Anti-Tumor Mechanism of Bajiaolian (Dysosma versipellis)[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (7) : 79 -85 . DOI: 10.13193/j.issn.1673-7717.2026.07.016
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Year 2026 volume 44 Issue 7
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Article Info
doi: 10.13193/j.issn.1673-7717.2026.07.016
  • Online Date：2026-10-20
  • Published：2026-07-10
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Affiliations
    1.The First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China
    2.Department of Microbiology and Immunology, Shanxi Medical University, Taiyuan 030001, Shanxi, China
    3.The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, Henan, China
    4.College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
    5.Henan Key Laboratory of Rare Diseases, Endocrinology and Metabolism Center, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang 471003, Henan, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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