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Outline
To explore the effect of Shugan Huayu Jieyu Decoction (疏肝化瘀解郁汤) combined with acupuncture on post-stroke depression and its influence on patients'physical and mental health.
A total of 119 patients with post-stroke depression admitted to the hospital from December 2020 to November 2023 were divided into groups by random number table method, and the patients were divided into western medicine group (59 cases) and traditional Chinese medicine group (60 cases). The patients in the western medicine group were treated with fluoxetine hydrochloride, and those in the traditional Chinese medicine group were treated with Shugan Huayu Jieyu Decoction combined with acupuncture therapy. The clinical efficacy and adverse reactions, traditional Chinese medicine symptom scores (depression, loss of interest, irritability, slow thinking, insomnia, fatigue, etc.) before and after treatment, Hamilton depression scale (HAMD) score and National Institute of Health stroke scale (NIHSS) score, the levels of norepinephrine (NE) and 5-hydroxytryptophan (5-HT), Pittsburgh sleep quality index (PSQI) and activities of daily living (ADL) scores of two groups were compared.
The total effective rate of traditional Chinese medicine group was 96.67%, which was higher than that of western medicine group (86.44%) (P<0.05). The adverse reaction rates of traditional Chinese medicine group and western medicine group were 3.33% and 3.39%, respectively, which were more tolerable by patients (P>0.05). Before treatment, traditional Chinese medicine syndrome scores (depression, loss of interest, irritability, slow thinking, insomnia, fatigue, etc.), HAMD score, NIHSS score, the levels of NE and 5-HT, PSQI score and ADL score were not significant in two groups (P>0.05). After treatment, traditional Chinese medicine syndrome scores (depression, loss of interest, irritability, slow thinking, insomnia, fatigue, etc.), HAMD scores, NIHSS scores, the levels of NE and 5-HT, PSQI scores and ADL scores were improved in two groups. After treatment, these indexes in traditional Chinese medicine group were all better than those in western medicine group (P<0.05).
The combination of Shugan Huayu Jieyu Decoction and acupuncture in the treatment of post-stroke depression is significant, safe and reliable.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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