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Clinical Efficacy and Mechanism of Acupuncture on Treatment of Cancerous Anorexia Nervosa by Regulating Du Meridian and Strengthening Spleen Method
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Hongchao LI1, Fangling LIU2, Xiaomei ZHANG3, Xue SUN1, Jinhuan HU1, Jianwei JIAO1, Lan WANG1, Xiaomei ZHOU1, Wendou HAN1, Jianlun LIAN1
Chinese Archives of Traditional Chinese Medicine | 2026, 44(6) : 223 - 226
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(6): 223-226
• Platform of Provincial Project •
Clinical Efficacy and Mechanism of Acupuncture on Treatment of Cancerous Anorexia Nervosa by Regulating Du Meridian and Strengthening Spleen Method
Full
Hongchao LI1, Fangling LIU2, Xiaomei ZHANG3, Xue SUN1, Jinhuan HU1, Jianwei JIAO1, Lan WANG1, Xiaomei ZHOU1, Wendou HAN1, Jianlun LIAN1
Affiliations
  • 1.Hebei Hospital of Traditional Chinese Medicine, Shijiazhuang 050000, Hebei, China
  • 2.Luanping County Hospital of Traditional Chinese Medicine, Chengde 068250, Hebei, China
  • 3.Xingtai Hospital of Traditional Chinese Medicine, Xingtai 054001, Hebei, China
Published: 2026-06-10 doi: 10.13193/j.issn.1673-7717.2026.06.042
Outline
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Objective

To observe the clinical efficacy of acupuncture in the treatment of anorexia nervosa with cancer by regulating Du meridian and strengthening spleen, and to explore the mechanism of its action.

Methods

The cases were included from October 2022 to June 2024, and 80 patients with anorexia nervosa with carcinoma attending the Department of Medical Oncology of the hospital were divided into the conventional group and the acupuncture group, each with 40 cases, using the random number table method. The conventional group was treated with conventional treatment of tumor, and the acupuncture group was treated with the acupuncture method of regulating Du meridian and strengthening spleen on the basis of the conventional treatment of tumor, and was treated continuously for 6 weeks. Body mass, quantitative appetite scale (NRS) scores, functional assessment of anorexia/malassemia treatment (FAACT) scores and traditional Chinese medicine syndrome scores and the levels of tumour necrosis factor-alpha (TNF-α), haemoglobin, albumin, interleukin-6 (IL-6), orexin A and leptin were compared between the two groups before and after treatment for 3 and 6 weeks and the clinical effect was evaluated.

Results

Before treatment, the differences in body mass, NRS scores, traditional Chinese medicine syndrome scores and FAACT scores were not statistically significant between two groups (P>0.05). Comparing 3 and 6 weeks of treatment with the pre-treatment period, the body mass and FAACT scores of the two groups increased, and the traditional Chinese medicine syndrome scores and NRS scores decreased (P<0.05). Comparing 3 and 6 weeks of treatment, the two groups had higher body mass and FAACT scores and lower traditional Chinese medicine syndrome scores and NRS scores than the conventional group (P<0.05). The differences in haemoglobin, albumin, TNF-α, IL-6, orexigenin A and leptin were not statistically significant between the two groups compared with those before treatment (P>0.05). Comparing 3 and 6 weeks of treatment with pre-treatment, the levels of haemoglobin, orexin A, albumin increased and TNF-α, IL-6 and leptin decreased in both groups (P<0.05) and those levels in the acupuncture group were significantly lower compared with those in the conventional group (P<0.05). The total effective rate of the acupuncture group (87.50%) was higher than that of the conventional group (67.50%), and the difference was statistically significant (P<0.05).

Conclusion

Acupuncture treatment of cancerous anorexia nervosa with the method of regulating Du meridian and strengthening spleen improves the nutritional status of the body and enhances the therapeutic efficacy, which may be related to the regulation of the neuro-endocrine network.

method of regulating Du meridian and strengthening spleen  /  acupuncture  /  cancer anorexia  /  clinical efficacy  /  neuro-endocrine network
李洪超, 刘方伶, 张晓梅, 孙雪, 胡金焕, 焦建玮, 王兰, 周晓梅, 韩文斗, 连建伦. 调督健脾法针刺治疗癌性厌食的临床观察及机制探究. 中华中医药学刊, 2026 , 44 (6) : 223 -226 . DOI: 10.13193/j.issn.1673-7717.2026.06.042
Hongchao LI, Fangling LIU, Xiaomei ZHANG, Xue SUN, Jinhuan HU, Jianwei JIAO, Lan WANG, Xiaomei ZHOU, Wendou HAN, Jianlun LIAN. Clinical Efficacy and Mechanism of Acupuncture on Treatment of Cancerous Anorexia Nervosa by Regulating Du Meridian and Strengthening Spleen Method[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (6) : 223 -226 . DOI: 10.13193/j.issn.1673-7717.2026.06.042
Year 2026 volume 44 Issue 6
72
16
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doi: 10.13193/j.issn.1673-7717.2026.06.042
  • Online Date:2026-10-14
  • Published:2026-06-10
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    1.Hebei Hospital of Traditional Chinese Medicine, Shijiazhuang 050000, Hebei, China
    2.Luanping County Hospital of Traditional Chinese Medicine, Chengde 068250, Hebei, China
    3.Xingtai Hospital of Traditional Chinese Medicine, Xingtai 054001, Hebei, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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