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Quality Control Status and Predictive Analysis of Quality Markers of Gusuibu (Drynaria fortunei Rhizoma)
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Zhidong MA1, 2, 3, 4, Jie LIANG1, 2, 3, 4, Jiali WEI1, 2, 3, 4, Sisi CHEN1, 2, 3, 4, Yuming MA1, 2, 3, 4, Jingjing XIE1, 2, 3, 4, Jiawen PENG1, 2, 3, 4, Zhengyi SUN5
Chinese Archives of Traditional Chinese Medicine | 2026, 44(6) : 20 - 25
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(6): 20-25
• Target on National Project •
Quality Control Status and Predictive Analysis of Quality Markers of Gusuibu (Drynaria fortunei Rhizoma)
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Zhidong MA1, 2, 3, 4, Jie LIANG1, 2, 3, 4, Jiali WEI1, 2, 3, 4, Sisi CHEN1, 2, 3, 4, Yuming MA1, 2, 3, 4, Jingjing XIE1, 2, 3, 4, Jiawen PENG1, 2, 3, 4, Zhengyi SUN5
Affiliations
  • 1.Guangxi University of Chinese Medicine, Guangxi Key Laboratory of Zhuang and Yao Ethnic Medicine, Nanning 530200, Guangxi, China
  • 2.Collaborative Innovation Center of Zhuang and Yao Ethnic Medicine, Nanning 530200, Guangxi, China
  • 3.Guangxi Zhuang Autonomous Region Ethnic Medicine Resources and Application Engineering Research Center, Nanning 530200, Guangxi, China
  • 4.Key Laboratory of TCM Extraction and Purification and Quality Analysis (Guangxi University of Chinese Medicine), Nanning 530200, Guangxi, China
  • 5.Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning 530011, Guangxi, China
Published: 2026-06-10 doi: 10.13193/j.issn.1673-7717.2026.06.004
Outline
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Gusuibu (Drynaria fortunei Rhizoma) contains flavonoids, phenylpropanoids, triterpenoids, phenolic acids and glycosides and other chemical components. Studies have shown that Gusuibu (Drynaria fortunei Rhizoma) has various pharmacological benefits, including anti-osteoporosis, accelerating the recovery of bone injury, reducing inflammation, promoting tooth growth, regulating blood lipid levels, preventing toxic ear injury, maintaining renal function, protecting nervous system health and improving cognitive functions. It has great potential and good development prospects. In this paper, the current situation of its quality control was briefly summarized. The 2020 edition of Chinese Pharmacopoeia uses naringin as the quality index component. At present, the quality control of Gusuibu (Drynaria fortunei Rhizoma) is single and the specificity is poor. Based on the concept of quality marker (Q-Marker) of traditional Chinese medicine, the potential quality markers of Gusuibu (Drynaria fortunei Rhizoma) were predicted and analyzed from eight aspects, including traditional medicinal properties, pharmacodynamics, pharmacokinetics, network pharmacology, different producing areas and processing methods, compound compatibility and new pharmacodynamic uses. It is preliminarily speculated that naringin, neoeriocitrin, luteolin, kaempferol, eriodictyol, naringenin, protocatechuic acid, 5-hydroxymethylfurfural and caffeic acid 4-O-β-D-glucopyranoside are the main Q-Markers of Gusuibu (Drynaria fortunei Rhizoma), which provides a scientific and reasonable reference for the construction of quality standard evaluation system of Gusuibu (Drynaria fortunei Rhizoma).

Gusuibu (Drynaria fortunei Rhizoma)  /  quality markers  /  predictive analysis
马志东, 梁洁, 韦佳丽, 陈思思, 马玉明, 谢晶晶, 彭嘉文, 孙正伊. 骨碎补的质量控制现状及质量标志物预测分析. 中华中医药学刊, 2026 , 44 (6) : 20 -25 . DOI: 10.13193/j.issn.1673-7717.2026.06.004
Zhidong MA, Jie LIANG, Jiali WEI, Sisi CHEN, Yuming MA, Jingjing XIE, Jiawen PENG, Zhengyi SUN. Quality Control Status and Predictive Analysis of Quality Markers of Gusuibu (Drynaria fortunei Rhizoma)[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (6) : 20 -25 . DOI: 10.13193/j.issn.1673-7717.2026.06.004
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Year 2026 volume 44 Issue 6
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doi: 10.13193/j.issn.1673-7717.2026.06.004
  • Online Date：2026-10-14
  • Published：2026-06-10
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Affiliations
    1.Guangxi University of Chinese Medicine, Guangxi Key Laboratory of Zhuang and Yao Ethnic Medicine, Nanning 530200, Guangxi, China
    2.Collaborative Innovation Center of Zhuang and Yao Ethnic Medicine, Nanning 530200, Guangxi, China
    3.Guangxi Zhuang Autonomous Region Ethnic Medicine Resources and Application Engineering Research Center, Nanning 530200, Guangxi, China
    4.Key Laboratory of TCM Extraction and Purification and Quality Analysis (Guangxi University of Chinese Medicine), Nanning 530200, Guangxi, China
    5.Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning 530011, Guangxi, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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