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Research Progress on Chemical Composition, Pharmacological Effects, Clinical Applications and Quality Marker Prediction of Qingning Powder (清宁散)
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Yongmei GUAN1, 3, Donghua PENG1, 3, Danfeng WANG2, 3, Zhiquan WANG2, 3, Lili XIONG2, 3, Zhenzhong ZANG1, Weifeng ZHU1, Yangming WU2, 3
Chinese Archives of Traditional Chinese Medicine | 2026, 44(6) : 5 - 14
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(6): 5-14
• New Opinion of Ph.D.Supervisor •
Research Progress on Chemical Composition, Pharmacological Effects, Clinical Applications and Quality Marker Prediction of Qingning Powder (清宁散)
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Yongmei GUAN1, 3, Donghua PENG1, 3, Danfeng WANG2, 3, Zhiquan WANG2, 3, Lili XIONG2, 3, Zhenzhong ZANG1, Weifeng ZHU1, Yangming WU2, 3
Affiliations
  • 1.Key Laboratory of Modern Traditional Chinese Medicine Preparations of Ministry of Education, Jiangxi University of Chinese Medicine, Nanchang 330004, Jiangxi, China
  • 2.Jiangzhong Pharmaceutical Co., Ltd, Nanchang 330006, Jiagnxi, China
  • 3.National Key Laboratory of Classic Formula and Modern Traditional Chinese Medicine Creation, Nanchang 330004, Jiangxi, China
Published: 2026-06-10 doi: 10.13193/j.issn.1673-7717.2026.06.002
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The classical formula Qingning Powder (清宁散) was originally documented in Youyou Jicheng by CHEN Fuzheng during the Qing Dynasty. It possesses the effects of clearing lung heat, calming the heart, purging lung fire and relieving cough. Modern research indicates that Qingning Powder exhibits anti-inflammatory and antitussive activities, and it is clinically applicable for treating pediatric lung-heat-induced cough and lung disorders caused by phlegm-heat accumulation and failure of purification and descent of lung. This paper provided a comprehensive review based on medical classics, modern literature and clinical research, covering the formula composition, chemical constituents and pharmacological activities of individual herbs, compound compatibility principles and modern clinical applications. Following the “Five Principles” of quality markers (Q-Markers) in traditional Chinese medicine, the potential Q-Markers for Qingning Powder were predicted and analyzed. The results suggest that geniposidic acid, verbascoside, 6-gingerol, betulinic acid, oleanolic acid, sanggenon B, mulberroside G, poricoic acid A, dehydrotumulosic acid, quercetin 3-O-β-D-glucosyl-7-O-β-D-gentianbioside, sinapic acid glucoside, morusin A and liquiritin may serve as the Q-Markers for Qingning Powder. This study offered a reference for the clinical application, pharmaceutical development and quality standard establishment of the classical formula Qingning Powder.

Qingning Powder (清宁散)  /  quality markers (Q-Markers)  /  chemical constituents  /  clinical application  /  formula compatibility
管咏梅, 彭冬华, 王丹凤, 王智权, 熊丽丽, 臧振中, 朱卫丰, 吴样明. 经典名方清宁散化学成分、药理作用、临床应用研究进展及质量标志物预测分析. 中华中医药学刊, 2026 , 44 (6) : 5 -14 . DOI: 10.13193/j.issn.1673-7717.2026.06.002
Yongmei GUAN, Donghua PENG, Danfeng WANG, Zhiquan WANG, Lili XIONG, Zhenzhong ZANG, Weifeng ZHU, Yangming WU. Research Progress on Chemical Composition, Pharmacological Effects, Clinical Applications and Quality Marker Prediction of Qingning Powder (清宁散)[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (6) : 5 -14 . DOI: 10.13193/j.issn.1673-7717.2026.06.002
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Year 2026 volume 44 Issue 6
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doi: 10.13193/j.issn.1673-7717.2026.06.002
  • Online Date：2026-10-14
  • Published：2026-06-10
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    1.Key Laboratory of Modern Traditional Chinese Medicine Preparations of Ministry of Education, Jiangxi University of Chinese Medicine, Nanchang 330004, Jiangxi, China
    2.Jiangzhong Pharmaceutical Co., Ltd, Nanchang 330006, Jiagnxi, China
    3.National Key Laboratory of Classic Formula and Modern Traditional Chinese Medicine Creation, Nanchang 330004, Jiangxi, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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