Tianma (Gastrodiae Rhizoma) has a long history of research and application as a traditional Chinese medicinal material. Traditional Chinese medicine believes that it has the effect of calming liver Yang, dispelling wind and dredging collateral, relieving wind and arresting convulsion, and is a Chinese herbal medicine often used in the treatment of ischemic stroke in clinical practice. The etiology and pathogenesis of ischemic stroke are complex, the clinical symptoms are recurrent, and the condition is lingering and difficult to heal, which seriously endangers the life, health and quality of life of the patients. Modern pharmacological studies have found that Tianma (Gastrodiae Rhizoma) and its active ingredients not only have anti-platelet aggregation, inhibit blood coagulation, reduce blood pressure, regulate blood lipids, protect nerve cells, vegetative tissue nerves and resist depression, but also can play the role of antioxidant stress, regulate immune inflammation and protect neurons through multiple pathways, so as to prevent and treat ischemic stroke. This article reviewed the mechanism and research of Tianma (Gastrodiae Rhizoma) and its active components in ischemic stroke, in order to provide reference for the clinical application and basic research of Tianma (Gastrodiae Rhizoma) in ischemic stroke.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |