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Research Progress of Chemical Composition, Pharmacological Effects and Clinical Application of Dayuan Decoction (达原饮) and Prediction of Its Quality Markers
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Jing ZHANG1, 2, Jianping ZHANG2, Dongying ZHAO2, Nengting HUANG2, 3, Yanying LI3, Xinyu ZANG2, 3, Jing HU1, 2, 3
Chinese Archives of Traditional Chinese Medicine | 2026, 44(5) : 193 - 203
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(5): 193-203
• Target on National Project •
Research Progress of Chemical Composition, Pharmacological Effects and Clinical Application of Dayuan Decoction (达原饮) and Prediction of Its Quality Markers
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Jing ZHANG1, 2, Jianping ZHANG2, Dongying ZHAO2, Nengting HUANG2, 3, Yanying LI3, Xinyu ZANG2, 3, Jing HU1, 2, 3
Affiliations
  • 1. School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
  • 2. Increasepharm (Tianjin) Innovative Medicine Institute Limited, Tianjin 300382, China
  • 3. Beijing Increasepharm Pharmaceutical Research Co., Ltd, Beijing 102200, China
Published: 2026-05-10 doi: 10.13193/j.issn.1673-7717.2026.05.036
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Dayuan Decoction (达原饮), a classic prescription, comes from The Theory ofEpidemic Fever written by WU Youke, a famous doctor in the Ming Dynasty. It is a representative prescription for treating epidemic diseases, which has the effects of opening onto the pleurodiaphragmatic interspace and repelling filth and transforming turbidity. It is widely used in modern clinic to treat viral infectious diseases, acute liver and lung injury, fever, insomnia and pediatric diseases. The chemical composition, pharmacological action and clinical application of Dayuan Decoction in recent years were summarized and the quality marker (Q-Marker) of this formula was predicted and analyzed according to the concept of Q-Marker. The results showed that arecoline, quercetin, magnolol, honokiol, epicatechin, protocatechuic acid, mangiferin, timosaponin AⅢ, paeoniflorin, albiflorin, benzoylpaeoniflorin, baicalin, baicalein, liquiritin, glycyrrhizicacid, glycyrrhetinic acid and isoliquiritigenin can be used as the Q-Markers, which could provide a reference for the quality control system and the development of Dayuan Decoction.

Dayuan Decoction (达原饮)  /  quality marker  /  chemical composition  /  pharmacological action  /  clinical application  /  quality control
张静, 张建平, 赵东颖, 黄能听, 李艳英, 臧新钰, 扈靖. 经典名方达原饮化学成分、药理作用、临床应用的研究进展及其质量标志物预测分析. 中华中医药学刊, 2026 , 44 (5) : 193 -203 . DOI: 10.13193/j.issn.1673-7717.2026.05.036
Jing ZHANG, Jianping ZHANG, Dongying ZHAO, Nengting HUANG, Yanying LI, Xinyu ZANG, Jing HU. Research Progress of Chemical Composition, Pharmacological Effects and Clinical Application of Dayuan Decoction (达原饮) and Prediction of Its Quality Markers[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (5) : 193 -203 . DOI: 10.13193/j.issn.1673-7717.2026.05.036
Appendix
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Year 2026 volume 44 Issue 5
102
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doi: 10.13193/j.issn.1673-7717.2026.05.036
  • Online Date：2026-10-14
  • Published：2026-05-10
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Affiliations
    1. School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
    2. Increasepharm (Tianjin) Innovative Medicine Institute Limited, Tianjin 300382, China
    3. Beijing Increasepharm Pharmaceutical Research Co., Ltd, Beijing 102200, China
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表12种不同金属材料的力学参数
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小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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