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Research Progress on Prevention of Osteoporosis by Duzhong (Cortex Eucommiae) and Its Active Ingredients
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Liang PEI1, Jirong ZHAO1, 2, Licun ZHANG1, Wenyuan FENG1, Wen CHEN3, Wentong YANG1, Weinong LI2
Chinese Archives of Traditional Chinese Medicine | 2026, 44(5) : 159 - 163
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(5): 159-163
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Research Progress on Prevention of Osteoporosis by Duzhong (Cortex Eucommiae) and Its Active Ingredients
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Liang PEI1, Jirong ZHAO1, 2, Licun ZHANG1, Wenyuan FENG1, Wen CHEN3, Wentong YANG1, Weinong LI2
Affiliations
  • 1. Gansu University of Chinese Medicine, Lanzhou 730000, Gansu, China
  • 2. Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730000, Gansu, China
  • 3. Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730000, Gansu, China
Published: 2026-05-10 doi: 10.13193/j.issn.1673-7717.2026.05.030
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The incidence of osteoporosis continues to climb under the dual influence of the rising proportion of the elderly population and the unregulated use of hormone drugs in China. As a traditional Chinese medicinal herb, Duzhong (Cortex Eucommiae) is well known for its ability to nourish liver and kidney, and strengthen the muscles and bones. Clinicians have widely used Duzhong (Cortex Eucommiae) in the treatment of osteoporosis, mainly due to its key active ingredients such as saponins, phenols and sterols. These components can effectively regulate the growth and differentiation of osteoblasts, influence the process of bone metabolism, optimise the internal environment of bones, and play a key role in the prevention and treatment of osteoporosis by influencing the Wnt/β-catenin signalling pathway, the MAPK signaling pathway, the cytokine signaling pathway related to bone metabolism, and the estrogen signaling pathway. In this paper, it provided an overview of the latest research progress of Duzhong (Cortex Eucommiae) and its active ingredients in the prevention and treatment of osteoporosis, aiming to provide new research directions for Chinese medicine in the prevention and treatment of this disease.

Duzhong (Cortex Eucommiae)  /  osteoporosis  /  bone metabolism  /  signaling pathways  /  literature review
裴亮, 赵继荣, 张立存, 冯文渊, 陈文, 杨文通, 李玮农. 杜仲及其有效成分防治骨质疏松的研究进展. 中华中医药学刊, 2026 , 44 (5) : 159 -163 . DOI: 10.13193/j.issn.1673-7717.2026.05.030
Liang PEI, Jirong ZHAO, Licun ZHANG, Wenyuan FENG, Wen CHEN, Wentong YANG, Weinong LI. Research Progress on Prevention of Osteoporosis by Duzhong (Cortex Eucommiae) and Its Active Ingredients[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (5) : 159 -163 . DOI: 10.13193/j.issn.1673-7717.2026.05.030
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Year 2026 volume 44 Issue 5
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doi: 10.13193/j.issn.1673-7717.2026.05.030
  • Online Date：2026-10-14
  • Published：2026-05-10
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    1. Gansu University of Chinese Medicine, Lanzhou 730000, Gansu, China
    2. Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730000, Gansu, China
    3. Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730000, Gansu, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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