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Outline
Baihuasheshecao (Herba Hedyotidis Diffusae) belongs to the genus Baihuasheshecao (Hedyotis diffusa) of the family Rubiaceae. It was first recorded in Luchuan Bencao. This herb has the effects of clearing away heat and detoxifying, reducing swelling and relieving pain. Baihuasheshecao (Herba Hedyotidis Diffusae) is clinically used for treating bruises, venomous snake bites and so on. Modern studies indicate that Baihuasheshecao (Herba Hedyotidis Diffusae) also exhibits anti-tumor pharmacological effects. Clinically, it is often employed to treat liver cancer, lung cancer, breast cancer, intestinal cancer and gastric cancer, particularly for digestive system tumors. The terpenoids, flavonoids and anthraquinones in Baihuasheshecao (Herba Hedyotidis Diffusae) could inhibit the malignant proliferation, invasion and metastasis of tumor cells, induce the apoptosis of tumor cells, block the signal pathway conduction and inhibit the angiogenesis. Moreover, Baihuasheshecao (Herba Hedyotidis Diffusae) can play an anti-tumor role by enhancing the body's immunity. In this manuscript, the active ingredients, pharmacological mechanisms and clinical applications of drug combinations of Baihuasheshecao (Herba Hedyotidis Diffusae) in the treatment of digestive system tumors were briefly reviewed, laying a foundation for the research and development of new drugs of Baihuasheshecao (Herba Hedyotidis Diffusae) for treating digestive system tumors.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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