Huangqin (Scutellariae Radix) is a particularly important medicinal material in the treasure trove of traditional Chinese medicine, with properties such as clearing heat and drying dampness, purging fire and removing toxin, stopping bleeding and tranquilizing the fetus. The main components in Huangqin (Scutellariae Radix) are flavonoids, volatile oils, organic acids and other compounds, with antibacterial, antiviral, anti-inflammatory, antioxidant, anti-tumor, liver protection, immunomodulation, neuroprotection and other pharmacological effects. This paper summarized the research progress on the chemical composition and pharmacological effects of Huangqin (Scutellariae Radix), and its quality markers (Q-markers) were predicted and analyzed based on the research of plant genetics and chemical composition specificity, correlation between traditional medicinal properties and efficacy, measurability of chemical composition, correlation between processing and chemical composition, pharmacokinetics and so on. The studies have shown that the main Q-markers of Huangqin (Scutellariae Radix) may include baicalin, baicalein, wogonoside, wogonin and other flavonoids, and these components are considered as the important indicators to evaluate the quality of Huangqin (Scutellariae Radix) due to their stable existence in Huangqin (Scutellariae Radix), clear pharmacological effects and reliable detection methods, which provide reference for the establishment of Huangqin (Scutellariae Radix) quality control system and clinical medication.

Huangqin (Scutellariae Radix)  /  chemical composition  /  pharmacological effects  /  quality markers  /  clinical medication