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Therapeutic Effect of Combination of Laonian Gusong Formula(老年骨松方)and Calcitriol on Elderly Patients with Osteoporotic Intertrochanteric Fractures of Femur
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Ou CHEN, Yunshuang HU, Bing XU
Chinese Archives of Traditional Chinese Medicine | 2026, 44(4) : 223 - 226
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(4): 223-226
• Platform of Provincial Project •
Therapeutic Effect of Combination of Laonian Gusong Formula(老年骨松方)and Calcitriol on Elderly Patients with Osteoporotic Intertrochanteric Fractures of Femur
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Ou CHEN, Yunshuang HU, Bing XU
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  • Wenzhou Hospital of Integrated Traditional Chinese Medicine, Wenzhou 325000, Zhejiang, China
Published: 2026-04-10 doi: 10.13193/j.issn.1673-7717.2026.04.043
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Objective

This study aims to assess the efficacy of Laonian Gusong Formula(老年骨松方)with calcitriol in treating the elderly patients with osteoporotic intertrochanteric fracture of the femur.

Method

A total of 160 elderly patients with osteoporotic intertrochanteric fractures of the femur were enrolled at the Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine from February 2022 to February 2024. The patients were randomly divided into a treatment group(80 cases) receiving Laonian Gusen Formula combined with calcitriol and a control group(80 cases)receiving calcitriol alone. The treatment lasted for 2 months. The therapeutic efficacy, pain relief[visual analogue scale(VAS)], bone mineral density(BMD), bone metabolism markers[insulin-like growth factor-1(IGF-1), growth hormone(GH), bone gla protein(BGP)], daily living ability[Barthel index(BI)]and complication rates were monitored and evaluated.

Results

The treatment group exhibited a significantly higher efficacy in traditional Chinese medicine syndrome treatment with a total effectiveness rate of 96.25%(77/80), compared to 77.50%(62/80)in the control group(P<0.05). Improvements in BI scores from 58.62 to 73.75 and reductions in VAS scores from 7.87 to 2.29 in the treatment group were significantly better than those in the control group(P<0.05). Furthermore, the bone density significantly increased in the treatment group, with the density measurements at the greater trochanter and femoral neck rising from 0.19 to 0.43 and from 0.43 to 0.49, respectively(P<0.000). Markers of bone metabolism such as IGF-1, GH and BGP also improved markedly(P<0.05). Additionally, the incidence of complications including pressure ulcers, infections and nausea was significantly lower in the treatment group at 5.00%(4/80)compared to 27.50%(22/80)in the control group(P<0.05).

Conclusion

The integration of Laonian Gusong Formula with calcitriol significantly enhances the bone density, alleviates the pain and promotes the functional recovery in the elderly patients with osteoporotic intertrochanteric fractures, proving to be an effective treatment strategy for these conditions.

osteoporosis intertrochanteric fracture of the femur  /  calcitriol  /  Laonian Gusong Formula(老年骨松方)  /  bone density
陈鸥, 胡云双, 许兵. 老年骨松方联合骨化三醇治疗老年骨质疏松性股骨粗隆间骨折疗效分析. 中华中医药学刊, 2026 , 44 (4) : 223 -226 . DOI: 10.13193/j.issn.1673-7717.2026.04.043
Ou CHEN, Yunshuang HU, Bing XU. Therapeutic Effect of Combination of Laonian Gusong Formula(老年骨松方)and Calcitriol on Elderly Patients with Osteoporotic Intertrochanteric Fractures of Femur[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (4) : 223 -226 . DOI: 10.13193/j.issn.1673-7717.2026.04.043
Year 2026 volume 44 Issue 4
93
22
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doi: 10.13193/j.issn.1673-7717.2026.04.043
  • Online Date:2026-10-14
  • Published:2026-04-10
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    Wenzhou Hospital of Integrated Traditional Chinese Medicine, Wenzhou 325000, Zhejiang, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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