Full
Outline
To investigate the clinical effect of Liujunzi Decoction（六君子汤）in the adjuvant treatment of children with bronchial asthma, and its effects on intestinal flora, corticotropin, corticosterone and microflora.
A total of 116 children with bronchial asthma admitted to the Department of Pediatrics of Jurong Hospital Affiliated to Jiangsu University from November 2022 to June 2024 were selected as the study objects. The patients were divided into two groups by random number table method, and 58 patients in the control group received conventional Western medicine treatment and those（58 patients）in the experimental group were treated with Liujunzi Decoction on the basis of conventional western medicine, all of whom were treated for 4 weeks. After treatment, the clinical effects, TCMsyndrome scores, intestinal flora, adrenocorticotropin and corticosterone before and after treatment were observed and compared between the two groups.
Compared with that（82.76%）of the control group, the overall curative effect was 96.55%（P<0.05）. Compared with those of the control group, the TCMsyndrome scores of the experimental group decreased more significantly（P<0.05）. Compared with those of the control group, the levels of corticotropin and corticosterone in the experimental group were lower（P<0.05）. Compared with those of the control group, bifidobacterium and lactobacillus in the experimental group were higher, and Escherichia coli was lower（P<0.05）. The detection rates of Staphylococcus aureus and Streptococcus virescens in the experimental group were lower than those in the control group（P<0.05）, and the detection rates of other bacteria groups were not statistically different between the two groups（P>0.05）.
After the adjuvant treatment of children with bronchial asthma with Liujunzi Decoction, the therapeutic effect is significantly improved, which can effectively improve the imbalance of intestinal flora and promote the recovery of children. It provides solid theoretical support for the clinical application of formulas and fosters the inheritance and innovation of traditional Chinese medicine.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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