To observe the clinical effect of acupuncture combined with Modified Liuwei Dihuang Pill(六味地黄丸加味)on the elderly stroke patients with hypertension(Yin deficiency of liver and kidney type)and its impact on blood pressure levels.
A hundred and ten elderly stroke patients with hypertension treated in the Traditional Chinese Medicine Department of The Affiliated Hospital of Air Force Medical University from January 2021 to January 2024 were randomly divided into a control group and an experimental group, with 55 patients in each group. The control group was treated with nifedipine controlled-release tablets, while the experimental group was treated with acupuncture combined with Modified Liuwei Dihuang Pills. The clinical efficacy, blood pressure, blood lipid levels and safety were compared between two groups.
The effective rate of the experimental group(94.55%, 52/55)was significantly better than that of the control group(83.64%, 46/55). Compared with those before intervention, the systolic and diastolic blood pressures of the patients in both groups were significantly reduced after 4 and 8 weeks of intervention(P < 0.05). Compared with those in the control group, the systolic and diastolic blood pressures of the patients in the experimental group were significantly reduced after intervention for 4 and 8 weeks(P < 0.05). Compared with those before intervention, the levels of TC, TG and LDL-C in both groups were significantly down-regulated after 4 and 8 weeks of intervention, while the level of HDL-C was significantly up-regulated(P < 0.05). Compared with those of the control group, the levels of TC, TG and levels of the experimental group were significantly down regulated after 4 and 8 weeks of intervention, while the HDL-C level was significantly up-regulated(P < 0.05). Compared with those before intervention, the NIHSS scores of both groups were significantly reduced after 4 and 8 weeks of intervention(P < 0.05). Compared with those of the control group, the NIHSS scores of the experimental group were significantly reduced after 4 and 8 weeks of intervention(P < 0.05). Compared with those before intervention, the SS-QOL scores of both groups were significantly up-regulated after 4 and 8 weeks of intervention(P < 0.05). Compared with those in the control group, the SS-QOL scores of the patients in the experimental group were significantly up-regulated after 4 and 8 weeks of intervention(P < 0.05). During the pre-treatment period, the main adverse reactions of the patients included nausea and vomiting, loss of appetite, palpitations and chest tightness, dizziness and headache, but there was no significant difference in the total incidence of adverse reactions between the two groups(P > 0.05).
Acupuncture combined with Modified Liuwei Dihuang Pills can achieve better clinical efficacy in the elderly stroke patients with hypertension(Yin deficiency of liver and kidney type). It can control the systolic and diastolic blood pressures more smoothly, reduce the blood lipids, improve the neurological and limb functions of the stroke patients, and has higher safety.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |