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Research Progress on Chemical Composition and Anti-Tumor Mechanism of Baizhu（Atractylodis Macrocephalae Rhizoma）
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Yumei ZHANG1, Jingyi WANG1, Siyuan CUI1, Kui LIU1, Wei ZHENG1, Zhenzhen WANG1, Jiyuan DING2
Chinese Archives of Traditional Chinese Medicine | 2026, 44(3) : 169 - 174
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Chinese Archives of Traditional Chinese Medicine | 2026, 44(3): 169-174
• Target on National Project •
Research Progress on Chemical Composition and Anti-Tumor Mechanism of Baizhu（Atractylodis Macrocephalae Rhizoma）
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Yumei ZHANG1, Jingyi WANG1, Siyuan CUI1, Kui LIU1, Wei ZHENG1, Zhenzhen WANG1, Jiyuan DING2
Affiliations
  • 1.Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250000, Shandong, China
  • 2.The First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250000, Shandong, China
Published: 2026-03-10 doi: 10.13193/j.issn.1673-7717.2026.03.031
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As the rhizome of the plant of Compositaceae, the traditional Chinese medicine Baizhu（Atractylodis Macrocephalae Rhizoma）has the effects of strengthening spleen and replenishing Qi, eliminating dampness and diuresis, anti-perspirant and miscarriage prevention. Its chemical active components mainly include lactones, polysaccharides, volatile oils, flavonoids, glycosides, etc. Modern pharmacological research shows that Baizhu（Atractylodis Macrocephalae Rhizoma）has the effects of regulating gastrointestinal tract, protecting cardiovascular and nervous system, protecting liver, anti-tumor, anti-inflammatory, anti-bacterial, anti-oxidant and regulating immunity and can be used for the treatment and prevention of gastrointestinal tract, nervous system, liver, tumor and other diseases. In this review, the anti-tumor mechanism of the main chemical components of Baizhu（Atractylodis Macrocephalae Rhizoma）was summarized. It can exert anti-tumor effects by inhibiting tumor cell proliferation, inducing tumor cell apoptosis, inhibiting tumor cell migration and invasion, blocking tumor cell cycle, inhibiting tumor neovascularization and regulating tumor microenvironment. The aim of this review was to provide important reference basis for the anti-tumor application of Baizhu（Atractylodis Macrocephalae Rhizoma）and its main chemical components.

Baizhu（Atractylodis Macrocephalae Rhizoma）  /  anti-tumor  /  cell proliferation  /  cell migration and invasion  /  apoptosis  /  cell cycle  /  tumor neovascularization  /  tumor microenvironment
张玉梅, 王敬毅, 崔思远, 刘奎, 郑伟, 王振振, 丁继元. 白术有效成分及抗肿瘤机制研究进展. 中华中医药学刊, 2026 , 44 (3) : 169 -174 . DOI: 10.13193/j.issn.1673-7717.2026.03.031
Yumei ZHANG, Jingyi WANG, Siyuan CUI, Kui LIU, Wei ZHENG, Zhenzhen WANG, Jiyuan DING. Research Progress on Chemical Composition and Anti-Tumor Mechanism of Baizhu（Atractylodis Macrocephalae Rhizoma）[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (3) : 169 -174 . DOI: 10.13193/j.issn.1673-7717.2026.03.031
Appendix
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Year 2026 volume 44 Issue 3
88
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doi: 10.13193/j.issn.1673-7717.2026.03.031
  • Online Date：2026-10-14
  • Published：2026-03-10
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    1.Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250000, Shandong, China
    2.The First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250000, Shandong, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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