To study the effect of Dingchuan Decoction（定喘汤）on TCM syndrome score and airway function in children with cough variant asthma（wind-heat attacking lung syndrome）.

A total of 120 children with cough variant asthma（wind-heat attacking lung syndrome）treated in the hospital from October 2023 to February 2024 were selected and divided into two groups according to the random number table method, with 60 cases in each group. The control group was treated with montelukast sodium, and the observation group was treated with Dingchuan Decoction on the basis of the control group. The course of treatment in both groups was 2 months. The efficacy, TCM syndrome scores, airway function parameters, inflammatory factors and adverse reactions were compared between the two groups.

The total effective rate of the observation group was 98.33%, which was significantly higher than 86.67% of the control group（P < 0.05）. After treatment, the scores of main TCM syndromes of asthma, cough and expectoration, chest tightness and irritability, red tongue and yellow moss in the two groups were significantly decreased, and the above scores in the observation group were significantly lower than those in the control group［（1.84 ± 0.33）points, （2.01 ± 0.75）points, （1.62 ± 0.28）points, （1.83 ± 0.26）points vs（2.40 ± 0.56）points, （2.42 ± 0.68）points, （2.05 ± 0.31）points, （2.04 ± 0.39）points］（P < 0.05）. After treatment. The percentage of forced expiratory volume in one second（FEV1%）, forced expiratory flow at 50% of FVC exhaled（FEF50）and forced expiratory flow at 50% of FVC exhaled（FEF75）were significantly increased. The above indexes in the observation group were significantly higher than those in the control group［（85.24 ± 7.91）%, （1.86 ± 0.46）L/s, （0.91 ± 0.20）L/s vs（82.30 ± 6.55）%, （1.69 ± 0.37）L/s, （0.82 ± 0.15）L/s］（P < 0.05）. After treatment, the levels of hypersensitive C-reactive protein（hs-CRP）, interleukin（IL）- 17 and IL-23 in the two groups were significantly decreased. The above indexes in the observation group were significantly lower than those in the control group［（7.08 ± 1.12）mg/L, （67.38 ± 7.89）ng/L, （21.36 ± 2.70）ng/L vs（10.31 ± 1.67）mg/L, （71.41 ± 6.59）ng/L, （26.08 ± 2.59）ng/L］（P < 0.05）. No serious adverse reactions occurred in both groups.

Dingchuan Decoction has a significant effect on children with cough variant asthma（wind-heat attacking lung syndrome）. It can more effectively alleviate various TCM syndromes, reduce the airway inflammation and improve the airway function. It is safe and worthy of application.