To analyze the clinical efficacy and regression of patients with severe acute respiratory distress syndrome treated with Modified Xuanbai Chengqi Decoction（宣白承气汤加减）.

A total of 120 patients with severe acute respiratory distress syndrome were selected for the study，60 cases of the control group were treated with conventional treatment，and 60 cases of the observation group were treated with auxiliary treatment of Modified Xuanbai Chengqi Decoction based on the above mentioned foundation. The blood gas indicators，traditional Chinese medicine syndrome scores，inflammatory factors，acute physiology and chronic health conditions（APACHE Ⅱ），sequential organ failure assessment（SOFA）scores，mechanical ventilation time and ICU stay time of the two groups were compared between the two groups.

The level of partial pressure of carbon dioxide（PaCO₂）of the observation group was lower than that of the control group and the levels of partial pressure of oxygen（PaO₂）and PaO₂/fraction of inspiration O₂（FiO₂）were higher than those of the control group after 3 d and 7 d of treatment（P<0.05）. The traditional Chinese medicine syndrome scores of the observation group were lower than those of the control group，and the time of mechanical ventilation and ICU hospitalization were shorter than those of the control group after treatment（P<0.05）. The levels of interleukin-1β（IL-1β），tumor necrosis factor-α（TNF-α）and interleukin-6（IL-6）of the observation group were lower than those of the control group after 3 d and 7 d of treatment（P<0.05）. The APACHE Ⅱ scores and SOFA scores were lower than those of the control group after treatment（P<0.05）.

The application of Modified Xuanbai Chengqi Decoction adjuvant treatment for patients with severe acute respiratory distress syndrome is conducive to improving the patients＇ oxygenation index and blood oxygen metabolism，enhancing the tissue circulation，regulating the levels of inflammatory factors，correcting the manifestations of respiratory distress and hypoxemia faster，and contributing to the improvement of the patients＇prognosis.