Full
Outline
To study the efficacy of Bushen Fangshu Decoction（补肾防疏汤）in the treatment of osteoporotic thoracolumbar compression fracture（kidney Qi deficiency syndrome）and its effect on fracture healing，and to analyze the related mechanism of action.
Ninety-eight patients with osteoporotic thoracolumbar compression fracture of kidney Qi deficiency syndrome who underwent surgical treatment in Weifang People's Hospital from January 2023 to January 2024 were included in the study，and they were divided into two groups by randomized numerical table method，49 cases of the control group were treated with conventional anti-osteoporosis therapy after surgery，and 49 cases of the observation group were treated with Bushen Fangshu Decoction on the basis of the control group，and the effect of the two groups was compared. The two groups were compared in terms of therapeutic effect，traditional Chinese medicine symptom scores，bone mineral density，lumbar spine function，pain level and bone metabolism index changes.
The total effective rate of the observation group was 95.92%，much higher than 77.55% of the control group，and the difference between the two groups was significant（P<0.05）. The points of the three main symptoms，lumbar spine function oswestry disability index（ODI）score，and fracture healing time of the observation group were lower than those of the control group（P<0.05）. The visual analog scale（VAS）scores of the observation group were lower than that of the control group in the 1-week，1-month，2-month and 3-month periods after surgery（P<0.05）. The levels of osteoporosis screening tool（OST），bone-specific alkaline phosphatase（BAP）and 25-hydroxyvitamin D［25（OH）D］and the bone mineral density of the observation group were higher than those of the control group after treatment（P<0.05）. VASscores at each time point were lower than those of the control group（P<0.05）. The levels of OST，BAP and 25（OH）D and the bone mineral density in the observation group were higher than those in the control group after treatment（P<0.05）.
The application of Bushen Fangshu Decoction for postoperative treatment of osteoporotic thoracolumbar compression fracture with kidney Qi deficiency syndrome can effectively reduce postoperative pain，improve bone density，promote bone metabolism，and has a positive effect on promoting functional recovery and improving quality of life for patients.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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