Chronic atrophic gastritis is a modern medical concept，which is categorized in traditional Chinese medicine as“epigastric pain”，“stuffiness of stomach”，“epigastric upset”and other diseases. The disease has the characteristics of insidious onset，long course and complexity. Most of the patients in the clinic show deficiency in origin and excess in superficislity，mix of cold and heat，and the prolonged disease often damages the positive Qi. And the real evils such as dampness，heat，blood stasis and other excess evils block the meridians and depletion of nutrient-Yin，and the loss of nourishment in the gastric mucosa leads to atrophy. Professor YAN Qinghai points out that according to his many years of clinical experience，chronic atrophic gastritis is the syndrome of deficiency in origin and excess in superficislity. The deficiency is Qi deficiency of spleen and stomach，leading to inability to transport and transform. The excess in superficislity is damp-heat obstructing the middle Jiao，or liver depression and Qi stagnation，liver-stomach disharmony，and poor circulation of Qi and blood. In the treatment of chronic atrophic gastritis，chronic atrophic gastritis is mostly treated with the basic principle of strengthening spleen and nourishing Qi，supplemented by methods such as clearing heat and dampness，soothing liver and harmonizing stomach. Combined with YAN Qinghai's own clinical practice，he has proposed a comprehensive treatment approach that combines tonifying，dispelling and regulating methods. Strengthening spleen，tonifying Qi，harmonizing stomach and descending adverse Qi，and clearing away heat and dampness are the common and effective methods for treating chronic atrophic gastritis. In this regard，Prof. YAN Qinghai has proposed the combination of disease differentiation and syndrome differentiation，the combination of macro and micro perspectives，the combination of treatment and mind regulation. The treatment combines the methods of treating the root，dispelling evil and dampness，and harmonizing spleen and stomach qi and blood. The patients' symptoms improved well and the clinical outcome was more significant.